| Host: | Rabbit |
| Applications: | CM/ELISA/ICC/IF/IHC/WB |
| Reactivity: | Human/Mouse/Rat |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description : | Rabbit polyclonal antibody anti-ADCY5 is suitable for use in Confocal Microscopy, ELISA, Immunocytochemistry, Immunofluorescence, Immunohistochemistry and Western Blot research applications. |
| Clonality : | Polyclonal |
| Conjugation: | FITC |
| Isotype: | IgG |
| Formulation: | Contains Tris, HCl/Glycine buffer pH 7.4-7.8, 30% Glycerol and 0.5% BSA, along with cryo-protective agents, Hepes, and long-term preservatives (0.02% Sodium Azide). |
| Purification: | Affinity Purified |
| Concentration: | 0.5 µg/µl |
| Dilution Range: | WB: 1:500DB: 1:10, 000ELISA: 1:10, 000IP: 1:200IHC: 1:200-1:1, 000ICC: 1:200-1:1, 000IF: 1:200-1:1, 000CFM: 1:200-1:1, 000 |
| Storage Instruction: | Store at-20°C for long term storage. Avoid freeze-thaw cycles. |
| Gene Symbol: | Adcy5 |
| Gene ID: | 64532 |
| Uniprot ID: | ADCY5_RAT |
| Immunogen: | Synthetic peptide corresponding to unique amino acid sequence on rat Particulate Adenylyl Cyclase 5 protein. |
| Tissue Specificity | Detected in brain and kidney. |
| Post Translational Modifications | Phosphorylated by RAF1. |
| Function | Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. Mediates signaling downstream of ADRB1. Regulates the increase of free cytosolic Ca(2+) in response to increased blood glucose levels and contributes to the regulation of Ca(2+)-dependent insulin secretion. |
| Protein Name | Adenylate Cyclase Type 5Atp Pyrophosphate-Lyase 5Adenylate Cyclase Type VAdenylyl Cyclase 5 |
| Database Links | Reactome: R-RNO-163615Reactome: -RNO-170660Reactome: -RNO-170670Reactome: -RNO-400042Reactome: -RNO-418597Reactome: -RNO-5610787 |
| Cellular Localisation | Cell MembraneMulti-Pass Membrane ProteinCell ProjectionCilium |
| Alternative Antibody Names | Anti-Adenylate Cyclase Type 5 antibodyAnti-Atp Pyrophosphate-Lyase 5 antibodyAnti-Adenylate Cyclase Type V antibodyAnti-Adenylyl Cyclase 5 antibodyAnti-Adcy5 antibody |
Information sourced from Uniprot.org
