Anti-ADCY5 antibody (471-521 aa) (STJ195830)
SPECIFICATIONS
ClonalityPolyclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
ImmunogenSynthesized peptide derived from the human ADCY5 at the amino acid range 471-521
General Information
| Short Description | Rabbit polyclonal anti-Adenylate cyclase type 5 (471-521 aa) for use in WB in Human, Mouse and Rat samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | WB |
| Host | Rabbit |
| Reactivity | Human/Mouse/Rat |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | 1 mg/mL |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Dilution Range | WB 1:500-2000 |
| Formulation | Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide. |
| Storage Instruction | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | ADCY5 |
| Gene ID | 111 |
| Uniprot ID | ADCY5_HUMAN |
| Immunogen | Synthesized peptide derived from the human ADCY5 at the amino acid range 471-521 |
| Immunogen Region | 471-521 aa |
| Specificity | This antibody detects endogenous levels of ADCY5 at Human/Mouse/Rat |
Additional Info
| Post Translational Modifications | Phosphorylated by RAF1. |
| Function | Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. Mediates signaling downstream of ADRB1. Regulates the increase of free cytosolic Ca(2+) in response to increased blood glucose levels and contributes to the regulation of Ca(2+)-dependent insulin secretion. |
| Protein Name | Adenylate Cyclase Type 5Atp Pyrophosphate-Lyase 5Adenylate Cyclase Type VAdenylyl Cyclase 5Ac5 |
| Database Links | Reactome: R-HSA-163359Reactome: R-HSA-163615Reactome: R-HSA-164378Reactome: R-HSA-170660Reactome: R-HSA-170670Reactome: R-HSA-381676Reactome: R-HSA-400042Reactome: R-HSA-418555Reactome: R-HSA-418594Reactome: R-HSA-418597Reactome: R-HSA-432040Reactome: R-HSA-5610787Reactome: R-HSA-9634597Reactome: R-HSA-9660821Reactome: R-HSA-9664323Reactome: R-HSA-9856530 |
| Cellular Localisation | Cell MembraneMulti-Pass Membrane ProteinCell ProjectionCilium |
| Alternative Antibody Names | Anti-Adenylate Cyclase Type 5 antibodyAnti-Atp Pyrophosphate-Lyase 5 antibodyAnti-Adenylate Cyclase Type V antibodyAnti-Adenylyl Cyclase 5 antibodyAnti-Ac5 antibodyAnti-ADCY5 antibody |
Information sourced from Uniprot.org