| Host: | Rabbit |
| Applications: | CM/ELISA/ICC/IF/IHC/IP/WB |
| Reactivity: | Human/Mouse/Rat |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description : | Rabbit polyclonal antibody anti-ADCY2 is suitable for use in Confocal Microscopy, ELISA, Immunocytochemistry, Immunofluorescence, Immunohistochemistry, Immunoprecipitation and Western Blot research applications. |
| Clonality : | Polyclonal |
| Conjugation: | FITC |
| Isotype: | IgG |
| Formulation: | Contains Tris, HCl/Glycine buffer pH 7.4-7.8, 30% Glycerol and 0.5% BSA, along with cryo-protective agents, Hepes, and long-term preservatives (0.02% Sodium Azide). |
| Purification: | Affinity Purified |
| Concentration: | 0.5 µg/µl |
| Dilution Range: | WB: 1:1, 000DB: 1:10, 000ELISA: 1:10, 000IP: 1:200IHC: 1:200ICC: 1:200IF: 1:200CFM: 1:200 |
| Storage Instruction: | Store at-20°C for long term storage. Avoid freeze-thaw cycles. |
| Gene Symbol: | Adcy2 |
| Gene ID: | 81636 |
| Uniprot ID: | ADCY2_RAT |
| Immunogen: | Synthetic peptide corresponding to unique amino acid sequence from rat Particulate Adenylyl Cyclase 2 protein. |
| Tissue Specificity | Expressed in brain, olfactory epithelium and lung. |
| Post Translational Modifications | Phosphorylated by RAF1. |
| Function | Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. Down-stream signaling cascades mediate changes in gene expression patterns and lead to increased IL6 production. Functions in signaling cascades downstream of the muscarinic acetylcholine receptors. |
| Protein Name | Adenylate Cyclase Type 2Atp Pyrophosphate-Lyase 2Adenylate Cyclase Type IiAdenylyl Cyclase 2Ac2 |
| Database Links | Reactome: R-RNO-163615Reactome: -RNO-170660Reactome: -RNO-170670Reactome: -RNO-418597Reactome: -RNO-5610787 |
| Cellular Localisation | MembraneMulti-Pass Membrane ProteinCell MembraneCytoplasm |
| Alternative Antibody Names | Anti-Adenylate Cyclase Type 2 antibodyAnti-Atp Pyrophosphate-Lyase 2 antibodyAnti-Adenylate Cyclase Type Ii antibodyAnti-Adenylyl Cyclase 2 antibodyAnti-Ac2 antibodyAnti-Adcy2 antibody |
Information sourced from Uniprot.org
