• Immunohistochemical analysis of paraffin-embedded human tonsil. 1, Antibody was diluted at 1:200 (4°C overnight). 2, Tris-EDTA, pH9.0 was used for antigen retrieval. 3, Secondary antibody was diluted at 1:200 (room temperature, 30min).

Anti-ADAMTS7 antibody (150-230 aa) (STJ91482)

SKU:
STJ91482

£46.00 - £226.00
Current Stock:
Host: Rabbit
Applications: IHC/IF/ELISA
Reactivity: Human/Rat/Mouse
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description: Rabbit polyclonal antibody anti-A disintegrin and metalloproteinase with thrombospondin motifs 7 (150-230 aa) is suitable for use in Immunohistochemistry, Immunofluorescence and ELISA research applications.
Clonality: Polyclonal
Conjugation: Unconjugated
Isotype: IgG
Formulation: Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide.
Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Concentration: 1 mg/mL
Dilution Range: IHC 1:100-1:300
ELISA 1:40000
IF 1:50-200
Storage Instruction: Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.
Gene Symbol: ADAMTS7
Gene ID: 11173
Uniprot ID: ATS7_HUMAN
Immunogen Region: 150-230 aa
Specificity: ADAMTS-7 Polyclonal Antibody detects endogenous levels of ADAMTS-7 protein.
Immunogen: Synthesized peptide derived from ADAMTS-7 at the amino acid range 150-230
Post Translational Modifications N-glycosylated. Can be O-fucosylated by POFUT2 on a serine or a threonine residue found within the consensus sequence C1-X(2)-(S/T)-C2-G of the TSP type-1 repeat domains where C1 and C2 are the first and second cysteine residue of the repeat, respectively. Fucosylated repeats can then be further glycosylated by the addition of a beta-1,3-glucose residue by the glucosyltransferase, B3GALTL. Fucosylation mediates the efficient secretion of ADAMTS family members. Can also be C-glycosylated with one or two mannose molecules on tryptophan residues within the consensus sequence W-X-X-W of the TPRs. N- and C-glycosylations can also facilitate secretion. O-glycosylated proteoglycan. Contains chondroitin sulfate. May be cleaved by a furin endopeptidase. The precursor is sequentially processed.
Function Metalloprotease that may play a role in the degradation of COMP.
Protein Name A Disintegrin And Metalloproteinase With Thrombospondin Motifs 7
Adam-Ts 7
Adam-Ts7
Adamts-7
Compase
Database Links Reactome: R-HSA-5083635
Reactome: R-HSA-5173214
Cellular Localisation Secreted
Extracellular Space
Extracellular Matrix
Also Found Associated With The External Cell Surface
Alternative Antibody Names Anti-A Disintegrin And Metalloproteinase With Thrombospondin Motifs 7 antibody
Anti-Adam-Ts 7 antibody
Anti-Adam-Ts7 antibody
Anti-Adamts-7 antibody
Anti-Compase antibody
Anti-ADAMTS7 antibody

Information sourced from Uniprot.org

12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance