| Host: |
Rabbit |
| Applications: |
WB/ELISA |
| Reactivity: |
Human/Rat/Mouse |
| Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description: |
Rabbit polyclonal antibody anti-A disintegrin and metalloproteinase with thrombospondin motifs 1 (160-240 aa) is suitable for use in Western Blot and ELISA research applications. |
| Clonality: |
Polyclonal |
| Conjugation: |
Unconjugated |
| Isotype: |
IgG |
| Formulation: |
Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide. |
| Purification: |
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Concentration: |
1 mg/mL |
| Dilution Range: |
WB 1:500-1:2000ELISA 1:5000 |
| Storage Instruction: |
Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: |
ADAMTS1 |
| Gene ID: |
9510 |
| Uniprot ID: |
ATS1_HUMAN |
| Immunogen Region: |
160-240 aa |
| Specificity: |
ADAMTS-1 Polyclonal Antibody detects endogenous levels of ADAMTS-1 protein. |
| Immunogen: |
Synthesized peptide derived from ADAMTS-1 at the amino acid range 160-240 |
| Function | Cleaves aggrecan, a cartilage proteoglycan, at the '1938-Glu-|-Leu-1939' site (within the chondroitin sulfate attachment domain), and may be involved in its turnover. Has angiogenic inhibitor activity. Active metalloprotease, which may be associated with various inflammatory processes as well as development of cancer cachexia. May play a critical role in follicular rupture. |
| Protein Name | A Disintegrin And Metalloproteinase With Thrombospondin Motifs 1Adam-Ts 1Adam-Ts1Adamts-1Meth-1 |
| Database Links | Reactome: R-HSA-1474228Reactome: R-HSA-5083635Reactome: R-HSA-5173214 |
| Cellular Localisation | SecretedExtracellular SpaceExtracellular Matrix |
| Alternative Antibody Names | Anti-A Disintegrin And Metalloproteinase With Thrombospondin Motifs 1 antibodyAnti-Adam-Ts 1 antibodyAnti-Adam-Ts1 antibodyAnti-Adamts-1 antibodyAnti-Meth-1 antibodyAnti-ADAMTS1 antibodyAnti-KIAA1346 antibodyAnti-METH1 antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
