| Host: | Rabbit |
| Applications: | WB/ELISA |
| Reactivity: | Human/Rat/Mouse |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description: | Rabbit polyclonal antibody anti-A disintegrin and metalloproteinase with thrombospondin motifs 1 (160-240 aa) is suitable for use in Western Blot and ELISA research applications. |
| Clonality: | Polyclonal |
| Conjugation: | Unconjugated |
| Isotype: | IgG |
| Formulation: | Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide. |
| Purification: | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Concentration: | 1 mg/mL |
| Dilution Range: | WB 1:500-1:2000 ELISA 1:5000 |
| Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: | ADAMTS1 |
| Gene ID: | 9510 |
| Uniprot ID: | ATS1_HUMAN |
| Immunogen Region: | 160-240 aa |
| Specificity: | ADAMTS-1 Polyclonal Antibody detects endogenous levels of ADAMTS-1 protein. |
| Immunogen: | Synthesized peptide derived from ADAMTS-1 at the amino acid range 160-240 |
| Function | Cleaves aggrecan, a cartilage proteoglycan, at the '1938-Glu-|-Leu-1939' site (within the chondroitin sulfate attachment domain), and may be involved in its turnover. Has angiogenic inhibitor activity. Active metalloprotease, which may be associated with various inflammatory processes as well as development of cancer cachexia. May play a critical role in follicular rupture. |
| Protein Name | A Disintegrin And Metalloproteinase With Thrombospondin Motifs 1 Adam-Ts 1 Adam-Ts1 Adamts-1 Meth-1 |
| Database Links | Reactome: R-HSA-1474228 Reactome: R-HSA-5083635 Reactome: R-HSA-5173214 |
| Cellular Localisation | Secreted Extracellular Space Extracellular Matrix |
| Alternative Antibody Names | Anti-A Disintegrin And Metalloproteinase With Thrombospondin Motifs 1 antibody Anti-Adam-Ts 1 antibody Anti-Adam-Ts1 antibody Anti-Adamts-1 antibody Anti-Meth-1 antibody Anti-ADAMTS1 antibody Anti-KIAA1346 antibody Anti-METH1 antibody |
Information sourced from Uniprot.org
