| Short Description : | Rabbit polyclonal ADAM8 (17-823) antibody for use in WB and ELISA in human, mouse and rat samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications: | WB/ELISA |
| Host: | Rabbit |
| Reactivity: | Human/Mouse/Rat |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Clonality : | Polyclonal |
| Isotype: | IgG |
| Conjugation: | Unconjugated |
| Concentration: | Lot specific |
| Purification: | Affinity purification |
| Dilution Range: | WB:1:500-1:1000ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Formulation: | PBS with 0.09% Sodium Azide, 50% Glycerol, pH 7.3. |
| Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: | ADAM8 |
| Gene ID: | 101 |
| Uniprot ID: | ADAM8_HUMAN |
| Immunogen Region: | 17-823 |
| Immunogen Sequence: | IAPSRPWALMEQYEVVLPWR LPGPRVRRALPSHLGLHPER VSYVLGATGHNFTLHLRKNR DLLGSGYTETYTAANGSEVT EQPRGQDHCFYQGHVEGYPD SAASLSTCAGLRGFFQVGSD LHLIEPLDEGGEGGRHAVYQ AEHLLQTAGTCGVSDDSLGS LLGPRTAAVFRPRPGDSLPS RETRYVELYVVVDNAEFQML GSEAAVRHRVLEVVNHVDKL YQKLNFRVVLVGLEIWNSQ |
| Specificity: | Recombinant fusion protein containing a sequence corresponding to amino acids 17-300 of human ADAM8 (NP_001100.3). |
| Tissue Specificity | Expressed on neutrophils and monocytes. |
| Function | Possible involvement in extravasation of leukocytes. |
| Protein Name | Disintegrin And Metalloproteinase Domain-Containing Protein 8Adam 8Cell Surface Antigen Ms2Cd Antigen Cd156a |
| Database Links | Reactome: R-HSA-1474228Reactome: R-HSA-6798695 |
| Cellular Localisation | MembraneSingle-Pass Type I Membrane Protein |
| Alternative Antibody Names | Anti-Disintegrin And Metalloproteinase Domain-Containing Protein 8 antibodyAnti-Adam 8 antibodyAnti-Cell Surface Antigen Ms2 antibodyAnti-Cd Antigen Cd156a antibodyAnti-ADAM8 antibodyAnti-MS2 antibody |
Information sourced from Uniprot.org
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