Anti-ADAM23 antibody (350-500) (STJ116476)
SPECIFICATIONS
ClonalityPolyclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
General Information
| Short Description | Rabbit polyclonal ADAM23 (350-500) antibody for use in WB and ELISA in human, mouse and rat samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | WB/ELISA |
| Host | Rabbit |
| Reactivity | Human/Mouse/Rat |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | Lot specific |
| Purification | Affinity purification |
| Dilution Range | WB:1:500-1:2000ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Formulation | PBS with 0.01% Thimerosal, 50% Glycerol, pH 7.3. |
| Storage Instruction | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | ADAM23 |
| Gene ID | 8745 |
| Uniprot ID | ADA23_HUMAN |
| Immunogen Region | 350-500 |
| Immunogen Sequence | VETWTEKDQIDITTNPVQML HEFSKYRQRIKQHADAVHLI SRVTFHYKRSSLSYFGGVCS RTRGVGVNEYGLPMAVAQVL SQSLAQNLGIQWEPSSRKPK CDCTESWGGCIMEETGVSHS RKFSKCSILEYRDFLQRGGG ACLFNRPTKLF |
| Specificity | Recombinant fusion protein containing a sequence corresponding to amino acids 350-500 of human ADAM23 (NP_003803.1). |
Additional Info
| Tissue Specificity | Highly expressed in the brain and weakly expressed in the heart. In the brain, expressed prominently in the amygdala, caudate nucleus, hypothalamus, thalamus, cerebral cortex and occipital pole. |
| Function | May play a role in cell-cell and cell-matrix interactions. This is a non-catalytic metalloprotease-like protein. |
| Protein Name | Disintegrin And Metalloproteinase Domain-Containing Protein 23Adam 23Metalloproteinase-Like - Disintegrin-Like - And Cysteine-Rich Protein 3Mdc-3 |
| Database Links | Reactome: R-HSA-5682910 |
| Cellular Localisation | Cell MembraneSingle-Pass Type I Membrane ProteinIsoform Gamma: Secreted |
| Alternative Antibody Names | Anti-Disintegrin And Metalloproteinase Domain-Containing Protein 23 antibodyAnti-Adam 23 antibodyAnti-Metalloproteinase-Like - Disintegrin-Like - And Cysteine-Rich Protein 3 antibodyAnti-Mdc-3 antibodyAnti-ADAM23 antibodyAnti-MDC3 antibody |
Information sourced from Uniprot.org