| Host: | Rabbit |
| Applications: | WB/ELISA |
| Reactivity: | Human/Mouse/Rat |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Clonality : | Polyclonal |
| Conjugation: | Unconjugated |
| Isotype: | IgG |
| Formulation: | PBS with 0.01% Thimerosal, 50% Glycerol, pH 7.3. |
| Purification: | Affinity purification |
| Concentration: | Lot specific |
| Dilution Range: | WB:1:500-1:2000ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: | ADAM23 |
| Gene ID: | 8745 |
| Uniprot ID: | ADA23_HUMAN |
| Immunogen Region: | 350-500 |
| Specificity: | Recombinant fusion protein containing a sequence corresponding to amino acids 350-500 of human ADAM23 (NP_003803.1). |
| Immunogen Sequence: | VETWTEKDQIDITTNPVQML HEFSKYRQRIKQHADAVHLI SRVTFHYKRSSLSYFGGVCS RTRGVGVNEYGLPMAVAQVL SQSLAQNLGIQWEPSSRKPK CDCTESWGGCIMEETGVSHS RKFSKCSILEYRDFLQRGGG ACLFNRPTKLF |
| Tissue Specificity | Highly expressed in the brain and weakly expressed in the heart. In the brain, expressed prominently in the amygdala, caudate nucleus, hypothalamus, thalamus, cerebral cortex and occipital pole. |
| Function | May play a role in cell-cell and cell-matrix interactions. This is a non-catalytic metalloprotease-like protein. |
| Protein Name | Disintegrin And Metalloproteinase Domain-Containing Protein 23Adam 23Metalloproteinase-Like - Disintegrin-Like - And Cysteine-Rich Protein 3Mdc-3 |
| Database Links | Reactome: R-HSA-5682910 |
| Cellular Localisation | Cell MembraneSingle-Pass Type I Membrane ProteinIsoform Gamma: Secreted |
| Alternative Antibody Names | Anti-Disintegrin And Metalloproteinase Domain-Containing Protein 23 antibodyAnti-Adam 23 antibodyAnti-Metalloproteinase-Like - Disintegrin-Like - And Cysteine-Rich Protein 3 antibodyAnti-Mdc-3 antibodyAnti-ADAM23 antibodyAnti-MDC3 antibody |
Information sourced from Uniprot.org