Anti-ADAM22 antibody (STJ192174)

SPECIFICATIONS
ClonalityPolyclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
ImmunogenSynthesized peptide derived from part of the human protein
STJ192174
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General Information

Short DescriptionRabbit polyclonal anti-Disintegrin and metalloproteinase domain-containing protein 22 for use in WB and ELISA in Human and Mouse samples. Datasheet included with dilution recommendations, and related reagents.
ApplicationsWB/ELISA
HostRabbit
ReactivityHuman/Mouse
NoteSTRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.

Product Properties

ClonalityPolyclonal
IsotypeIgG
ConjugationUnconjugated
Concentration1 mg/mL
PurificationThe antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Dilution RangeWB 1:500-2000
ELISA 1:5000-20000
FormulationLiquid in PBS containing 50% Glycerol and 0.02% Sodium Azide.
Storage InstructionStore at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.

Target Information

Gene SymbolADAM22
Gene ID53616
Uniprot IDADA22_HUMAN
ImmunogenSynthesized peptide derived from part of the human protein
SpecificityADA22 Polyclonal Antibody detects endogenous levels of protein.

Additional Info

Post Translational Modifications The precursor is cleaved by a furin endopeptidase.
Function Probable ligand for integrin in the brain. This is a non catalytic metalloprotease-like protein. Involved in regulation of cell adhesion and spreading and in inhibition of cell proliferation. Neuronal receptor for LGI1.
Protein Name Disintegrin And Metalloproteinase Domain-Containing Protein 22
Adam 22
Metalloproteinase-Disintegrin Adam22-3
Metalloproteinase-Like - Disintegrin-Like - And Cysteine-Rich Protein 2
Database Links Reactome: R-HSA-5682910
Cellular Localisation Cell Membrane
Single-Pass Type I Membrane Protein
Cell Projection
Axon
Alternative Antibody Names Anti-Disintegrin And Metalloproteinase Domain-Containing Protein 22 antibody
Anti-Adam 22 antibody
Anti-Metalloproteinase-Disintegrin Adam22-3 antibody
Anti-Metalloproteinase-Like - Disintegrin-Like - And Cysteine-Rich Protein 2 antibody
Anti-ADAM22 antibody
Anti-MDC2 antibody

Information sourced from Uniprot.org

Citations

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