Anti-ADAM2 antibody (109-159 aa) (STJ194448)
SPECIFICATIONS
ClonalityPolyclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
ImmunogenSynthesized peptide derived from the human ADAM2 at the amino acid range 109-159
General Information
| Short Description | Rabbit polyclonal anti-Disintegrin and metalloproteinase domain-containing protein 2 (109-159 aa) for use in WB in Human, Mouse and Rat samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | WB |
| Host | Rabbit |
| Reactivity | Human/Mouse/Rat |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | 1 mg/mL |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Dilution Range | WB 1:500-2000 |
| Formulation | Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide. |
| Storage Instruction | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | ADAM2 |
| Gene ID | 2515 |
| Uniprot ID | ADAM2_HUMAN |
| Immunogen | Synthesized peptide derived from the human ADAM2 at the amino acid range 109-159 |
| Immunogen Region | 109-159 aa |
| Specificity | This antibody detects endogenous levels of ADAM2 at Human/Mouse/Rat |
Additional Info
| Post Translational Modifications | The prodomain and the metalloprotease domain are cleaved during the epididymal maturation of the spermatozoa. |
| Function | Sperm surface membrane protein that may be involved in sperm-egg plasma membrane adhesion and fusion during fertilization. Could have a direct role in sperm-zona binding or migration of sperm from the uterus into the oviduct. Interactions with egg membrane could be mediated via binding between its disintegrin-like domain to one or more integrins receptors on the egg. This is a non catalytic metalloprotease-like protein. |
| Protein Name | Disintegrin And Metalloproteinase Domain-Containing Protein 2Adam 2Cancer/Testis Antigen 15Ct15Fertilin Subunit BetaPh-30Ph30Ph30-Beta |
| Database Links | Reactome: R-HSA-2534343 |
| Cellular Localisation | MembraneSingle-Pass Type I Membrane Protein |
| Alternative Antibody Names | Anti-Disintegrin And Metalloproteinase Domain-Containing Protein 2 antibodyAnti-Adam 2 antibodyAnti-Cancer/Testis Antigen 15 antibodyAnti-Ct15 antibodyAnti-Fertilin Subunit Beta antibodyAnti-Ph-30 antibodyAnti-Ph30 antibodyAnti-Ph30-Beta antibodyAnti-ADAM2 antibodyAnti-FTNB antibody |
Information sourced from Uniprot.org