Host: |
Goat |
Applications: |
Pep-ELISA/WB |
Reactivity: |
Human/Mouse/Rat/Pig/Cow |
Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Short Description: |
Goat polyclonal antibody anti-ADAM12 (225-239) is suitable for use in ELISA and Western Blot research applications. |
Clonality: |
Polyclonal |
Conjugation: |
Unconjugated |
Isotype: |
IgG |
Formulation: |
0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin. NA |
Purification: |
Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide. |
Concentration: |
0.5 mg/mL |
Dilution Range: |
WB-0.1-0.3µg/mlELISA-antibody detection limit dilution 1:128000. |
Storage Instruction: |
Store at-20°C on receipt and minimise freeze-thaw cycles. |
Gene Symbol: |
ADAM12 |
Gene ID: |
8038 |
Uniprot ID: |
ADA12_HUMAN |
Immunogen Region: |
225-239 |
Accession Number: |
NP_003465.3; NP_067673.2 |
Specificity: |
This antibody is expected to recognize both reported isoforms (NP_003465.3; NP_067673.2). |
Immunogen Sequence: |
REFQRQGKDLEKVKQ |
Post Translational Modifications | The precursor is cleaved by a furin endopeptidase. |
Function | Involved in skeletal muscle regeneration, specifically at the onset of cell fusion. Also involved in macrophage-derived giant cells (MGC) and osteoclast formation from mononuclear precursors. |
Protein Name | Disintegrin And Metalloproteinase Domain-Containing Protein 12Adam 12Meltrin-Alpha |
Database Links | Reactome: R-HSA-177929Reactome: R-HSA-8941237 |
Cellular Localisation | Isoform 1: Cell MembraneSingle-Pass Type I Membrane ProteinIsoform 2: SecretedIsoform 3: SecretedIsoform 4: Secreted |
Alternative Antibody Names | Anti-Disintegrin And Metalloproteinase Domain-Containing Protein 12 antibodyAnti-Adam 12 antibodyAnti-Meltrin-Alpha antibodyAnti-ADAM12 antibodyAnti-MLTN antibodyAnti-UNQ346 antibodyAnti-PRO545 antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance