• Western blot analysis of extracts of various cell lines, using ACY3 antibody (STJ116275) at 1:3000 dilution. Secondary antibody: HRP Goat Anti-rabbit IgG (H+L) at 1:10000 dilution. Lysates/proteins: 25ug per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit. Exposure time: 90s.

Anti-ACY3 antibody (1-319) (STJ116275)

SKU:
STJ116275

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Host: Rabbit
Applications: WB
Reactivity: Mouse
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description: Rabbit polyclonal antibody anti-ACY3 (1-319) is suitable for use in Western Blot research applications.
Clonality: Polyclonal
Conjugation: Unconjugated
Isotype: IgG
Formulation: PBS with 0.02% Sodium Azide, 50% Glycerol, pH7.3.
Purification: Affinity purification
Dilution Range: WB 1:500-1:2000
Storage Instruction: Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.
Gene Symbol: ACY3
Gene ID: 91703
Uniprot ID: ACY3_HUMAN
Immunogen Region: 1-319
Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 1-319 of human ACY3 (NP_542389.1).
Immunogen Sequence: MCSLPVPREPLRRVAVTGGT HGNEMSGVYLARHWLHAPAE LQRASFSAVPVLANPAATSG CRRYVDHDLNRTFTSSFLNS RPTPDDPYEVTRARELNQLL GPKASGQAFDFVLDLHNTTA NMGTCLIAKSSHEVFAMHLC RHLQLQYPELSCQVFLYQRS GEESYNLDSVAKNGLGLELG PQPQGVLRADIFSRMRTLVA TVLDFIELFNQGTAFPAFEM EAYRPVGVVDFPRTEAGHL
Function Plays an important role in deacetylating mercapturic acids in kidney proximal tubules. Also acts on N-acetyl-aromatic amino acids.
Protein Name N-Acyl-Aromatic-L-Amino Acid Amidohydrolase
Carboxylate-Forming
Acylase Iii
Aminoacylase-3
Acy-3
Aspartoacylase-2
Hepatitis C Virus Core-Binding Protein 1
Hcbp1
Hcv Core-Binding Protein 1
Database Links Reactome: R-HSA-5423646
Cellular Localisation Apical Cell Membrane
Peripheral Membrane Protein
Cytoplasm
Predominantly Localized In The Apical Membrane Of Cells In The S1 Segment
In The Proximal Straight Tubules (S2 And S3 Segments) Is Expressed Diffusely Throughout The Cytoplasm
Alternative Antibody Names Anti-N-Acyl-Aromatic-L-Amino Acid Amidohydrolase antibody
Anti-Carboxylate-Forming antibody
Anti-Acylase Iii antibody
Anti-Aminoacylase-3 antibody
Anti-Acy-3 antibody
Anti-Aspartoacylase-2 antibody
Anti-Hepatitis C Virus Core-Binding Protein 1 antibody
Anti-Hcbp1 antibody
Anti-Hcv Core-Binding Protein 1 antibody
Anti-ACY3 antibody
Anti-ASPA2 antibody

Information sourced from Uniprot.org

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