| Host: | Rabbit |
| Applications: | WB |
| Reactivity: | Human/Mouse/Rat |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description : | Rabbit polyclonal anti-Actin-related protein T1 (241-291 aa) for use in WB in Human, Mouse and Rat samples. Datasheet included with dilution recommendations, and related reagents. |
| Clonality : | Polyclonal |
| Conjugation: | Unconjugated |
| Isotype: | IgG |
| Formulation: | Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide. |
| Purification: | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Concentration: | 1 mg/mL |
| Dilution Range: | WB 1:500-2000 |
| Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: | ACTRT1 |
| Gene ID: | 139741 |
| Uniprot ID: | ACTT1_HUMAN |
| Immunogen Region: | 241-291 aa |
| Specificity: | This antibody detects endogenous levels of ACTT1 at Human/Mouse/Rat |
| Immunogen: | Synthesized peptide derived from the human ACTT1 at the amino acid range 241-291 |
| Function | Negatively regulates the Hedgehog (SHH) signaling. Binds to the promoter of the SHH signaling mediator, GLI1, and inhibits its expression. |
| Protein Name | Actin-Related Protein T1Arp-T1 |
| Database Links | |
| Cellular Localisation | CytoplasmCytoskeletonNucleusCytoplasmic VesicleSecretory VesicleAcrosomeBoth Detected In The Nucleus And CytoplasmLocalizes To The Nucleus Where It Binds Chromatin Upon Stimulation Of The Hedgehog Pathway |
| Alternative Antibody Names | Anti-Actin-Related Protein T1 antibodyAnti-Arp-T1 antibodyAnti-ACTRT1 antibodyAnti-ARPT1 antibodyAnti-HSD27 antibody |
Information sourced from Uniprot.org
