| Host: | Rabbit |
| Applications: | WB/IHC-P/ELISA |
| Reactivity: | Human/Mouse/Rat |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Clonality : | Polyclonal |
| Conjugation: | Unconjugated |
| Isotype: | IgG |
| Formulation: | PBS with 0.01% Thimerosal, 50% Glycerol, pH 7.3. |
| Purification: | Affinity purification |
| Concentration: | Lot specific |
| Dilution Range: | WB:1:500-1:2000IHC-P:1:100-1:500ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: | ACTN3 |
| Gene ID: | 89 |
| Uniprot ID: | ACTN3_HUMAN |
| Immunogen Region: | 580-630 |
| Specificity: | Recombinant fusion protein containing a sequence corresponding to amino acids 580-630 of human ACTN3 (NP_001095.2). |
| Immunogen Sequence: | GAIMGIQGEIQKICQTYGLR PCSTNPYITLSPQDINTKWD MVRKLVPSCDQ |
| Tissue Specificity | Expression restricted to fast (type 2) skeletal muscle fibers (at protein level). |
| Function | F-actin cross-linking protein which is thought to anchor actin to a variety of intracellular structures. This is a bundling protein. |
| Protein Name | Alpha-Actinin-3Alpha-Actinin Skeletal Muscle Isoform 3F-Actin Cross-Linking Protein |
| Database Links | Reactome: R-HSA-373753Reactome: R-HSA-390522 |
| Alternative Antibody Names | Anti-Alpha-Actinin-3 antibodyAnti-Alpha-Actinin Skeletal Muscle Isoform 3 antibodyAnti-F-Actin Cross-Linking Protein antibodyAnti-ACTN3 antibody |
Information sourced from Uniprot.org