Anti-ACSL6 antibody (383-622) (STJ110272)
SPECIFICATIONS
ClonalityPolyclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
General Information
| Short Description | Rabbit polyclonal ACSL6 (383-622) antibody for use in WB and ELISA in human, mouse and rat samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | WB/ELISA |
| Host | Rabbit |
| Reactivity | Human/Mouse/Rat |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | Lot specific |
| Purification | Affinity purification |
| Dilution Range | WB:1:500-1:2000ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Formulation | PBS with 0.02% Sodium Azide, 50% Glycerol, pH 7.3. |
| Storage Instruction | Store at-20ยฐC for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | ACSL6 |
| Gene ID | 23305 |
| Uniprot ID | ACSL6_HUMAN |
| Immunogen Region | 383-622 |
| Immunogen Sequence | YGQTECTAGCTFTTPGDWTS GHVGAPLPCNHIKLVDVEEL NYWACKGEGEICVRGPNVFK GYLKDPDRTKEALDSDGWLH TGDIGKWLPAGTLKIIDRKK HIFKLAQGEYVAPEKIENIY IRSQPVAQIYVHGDSLKAFL VGIVVPDPEVMPSWAQKRGI EGTYADLCTNKDLKKAILED MVRLGKESGLHSFEQVKAIH IHSDMFSVQNGLLTPTLKAK RPELREYFKKQIEELYSIS |
| Specificity | Recombinant fusion protein containing a sequence corresponding to amino acids 383-622 of human ACSL6 (NP_001192180.1). |
Additional Info
| Tissue Specificity | Expressed predominantly in erythrocyte precursors, in particular in reticulocytes, fetal blood cells derived from fetal liver, hemopoietic stem cells from cord blood, bone marrow and brain. |
| Function | Catalyzes the conversion of long-chain fatty acids to their active form acyl-CoA for both synthesis of cellular lipids, and degradation via beta-oxidation. Plays an important role in fatty acid metabolism in brain and the acyl-CoAs produced may be utilized exclusively for the synthesis of the brain lipid. |
| Protein Name | Long-Chain-Fatty-Acid--Coa Ligase 6Arachidonate--Coa LigaseLong-Chain Acyl-Coa Synthetase 6Lacs 6 |
| Database Links | Reactome: R-HSA-75876 |
| Cellular Localisation | Mitochondrion Outer MembraneSingle-Pass Type Iii Membrane ProteinPeroxisome MembraneMicrosome MembraneEndoplasmic Reticulum Membrane |
| Alternative Antibody Names | Anti-Long-Chain-Fatty-Acid--Coa Ligase 6 antibodyAnti-Arachidonate--Coa Ligase antibodyAnti-Long-Chain Acyl-Coa Synthetase 6 antibodyAnti-Lacs 6 antibodyAnti-ACSL6 antibodyAnti-ACS2 antibodyAnti-FACL6 antibodyAnti-KIAA0837 antibodyAnti-LACS5 antibody |
Information sourced from Uniprot.org