| Host: | Rabbit |
| Applications: | WB/ELISA |
| Reactivity: | Human/Mouse/Rat |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Clonality : | Polyclonal |
| Conjugation: | Unconjugated |
| Isotype: | IgG |
| Formulation: | PBS with 0.02% Sodium Azide, 50% Glycerol, pH 7.3. |
| Purification: | Affinity purification |
| Concentration: | Lot specific |
| Dilution Range: | WB:1:500-1:2000ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: | ACSL6 |
| Gene ID: | 23305 |
| Uniprot ID: | ACSL6_HUMAN |
| Immunogen Region: | 383-622 |
| Specificity: | Recombinant fusion protein containing a sequence corresponding to amino acids 383-622 of human ACSL6 (NP_001192180.1). |
| Immunogen Sequence: | YGQTECTAGCTFTTPGDWTS GHVGAPLPCNHIKLVDVEEL NYWACKGEGEICVRGPNVFK GYLKDPDRTKEALDSDGWLH TGDIGKWLPAGTLKIIDRKK HIFKLAQGEYVAPEKIENIY IRSQPVAQIYVHGDSLKAFL VGIVVPDPEVMPSWAQKRGI EGTYADLCTNKDLKKAILED MVRLGKESGLHSFEQVKAIH IHSDMFSVQNGLLTPTLKAK RPELREYFKKQIEELYSIS |
| Tissue Specificity | Expressed predominantly in erythrocyte precursors, in particular in reticulocytes, fetal blood cells derived from fetal liver, hemopoietic stem cells from cord blood, bone marrow and brain. |
| Function | Catalyzes the conversion of long-chain fatty acids to their active form acyl-CoA for both synthesis of cellular lipids, and degradation via beta-oxidation. Plays an important role in fatty acid metabolism in brain and the acyl-CoAs produced may be utilized exclusively for the synthesis of the brain lipid. |
| Protein Name | Long-Chain-Fatty-Acid--Coa Ligase 6Arachidonate--Coa LigaseLong-Chain Acyl-Coa Synthetase 6Lacs 6 |
| Database Links | Reactome: R-HSA-75876 |
| Cellular Localisation | Mitochondrion Outer MembraneSingle-Pass Type Iii Membrane ProteinPeroxisome MembraneMicrosome MembraneEndoplasmic Reticulum Membrane |
| Alternative Antibody Names | Anti-Long-Chain-Fatty-Acid--Coa Ligase 6 antibodyAnti-Arachidonate--Coa Ligase antibodyAnti-Long-Chain Acyl-Coa Synthetase 6 antibodyAnti-Lacs 6 antibodyAnti-ACSL6 antibodyAnti-ACS2 antibodyAnti-FACL6 antibodyAnti-KIAA0837 antibodyAnti-LACS5 antibody |
Information sourced from Uniprot.org