| Host: | Rabbit |
| Applications: | WB/IHC-P/ELISA |
| Reactivity: | Human/Mouse |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Clonality : | Polyclonal |
| Conjugation: | Unconjugated |
| Isotype: | IgG |
| Formulation: | PBS with 0.05% Proclin300, 50% Glycerol, pH 7.3. |
| Purification: | Affinity purification |
| Concentration: | Lot specific |
| Dilution Range: | WB:1:500-1:1000 IHC-P:1:50-1:200 ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: | ACOX2 |
| Gene ID: | 8309 |
| Uniprot ID: | ACOX2_HUMAN |
| Immunogen Region: | 1-150 |
| Specificity: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-150 of human ACOX2 (NP_003491.1). |
| Immunogen Sequence: | MGSPVHRVSLGDTWSRQMHP DIESERYMQSFDVERLTNIL DGGAQNTALRRKVESIIHSY PEFSCKDNYFMTQNERYKAA MRRAFHIRLIARRLGWLEDG RELGYAYRALSGDVALNIHR VFVRALRSLGSEEQIAKWDP LCKNIQIIAT |
| Tissue Specificity | Present in all tissues tested: heart, brain, placenta, lung, liver, skeletal muscle, kidney and pancreas. Most abundant in heart, liver and kidney. |
| Function | Oxidizes the CoA esters of the bile acid intermediates di- and tri-hydroxycholestanoic acids. Capable of oxidizing short as well as long chain 2-methyl branched fatty acids. |
| Protein Name | Peroxisomal Acyl-Coenzyme A Oxidase 2 3-Alpha -7-Alpha -12-Alpha-Trihydroxy-5-Beta-Cholestanoyl-Coa 24-Hydroxylase 3-Alpha -7-Alpha -12-Alpha-Trihydroxy-5-Beta-Cholestanoyl-Coa Oxidase Trihydroxycoprostanoyl-Coa Oxidase Thca-Coa Oxidase Thccox |
| Database Links | Reactome: R-HSA-193368 Reactome: R-HSA-389887 Reactome: R-HSA-9033241 |
| Cellular Localisation | Peroxisome |
| Alternative Antibody Names | Anti-Peroxisomal Acyl-Coenzyme A Oxidase 2 antibody Anti-3-Alpha -7-Alpha -12-Alpha-Trihydroxy-5-Beta-Cholestanoyl-Coa 24-Hydroxylase antibody Anti-3-Alpha -7-Alpha -12-Alpha-Trihydroxy-5-Beta-Cholestanoyl-Coa Oxidase antibody Anti-Trihydroxycoprostanoyl-Coa Oxidase antibody Anti-Thca-Coa Oxidase antibody Anti-Thccox antibody Anti-ACOX2 antibody |
Information sourced from Uniprot.org