Anti-ACOX1 antibody (STJA0006738)
SPECIFICATIONS
ClonalityPolyclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
ImmunogenSynthesized peptide derived from human ACOX1
General Information
| Short Description | Rabbit polyclonal anti-Peroxisomal acyl-coenzyme A oxidase 1 for use in WB in Human, Mouse and Rat samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | WB |
| Host | Rabbit |
| Reactivity | Human/Mouse/Rat |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | 1 mg/mL |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Dilution Range | WB 1:500-2000 |
| Formulation | Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide. |
| Storage Instruction | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | ACOX1 |
| Gene ID | 51 |
| Uniprot ID | ACOX1_HUMAN |
| Immunogen | Synthesized peptide derived from human ACOX1 |
| Specificity | This antibody detects endogenous levels of ACOX1 at Human, Mouse, Rat |
Additional Info
| Function | Involved in the initial and rate-limiting step of peroxisomal beta-oxidation of straight-chain saturated and unsaturated very-long-chain fatty acids. Catalyzes the desaturation of fatty acyl-CoAs such as palmitoyl-CoA (hexadecanoyl-CoA) to 2-trans-enoyl-CoAs ((2E)-enoyl-CoAs) such as (2E)-hexadecenoyl-CoA, and donates electrons directly to molecular oxygen (O(2)), thereby producing hydrogen peroxide (H(2)O(2)). Isoform 1: Shows highest activity against medium-chain fatty acyl-CoAs. Shows optimum activity with a chain length of 10 carbons (decanoyl-CoA) in vitro. Isoform 2: Is active against a much broader range of substrates and shows activity towards long-chain fatty acyl-CoAs. |
| Protein Name | Peroxisomal Acyl-Coenzyme A Oxidase 1AoxPalmitoyl-Coa OxidasePeroxisomal Fatty Acyl-Coa OxidaseStraight-Chain Acyl-Coa OxidaseScox Cleaved Into - Peroxisomal Acyl-Coa Oxidase 1 - A Chain - Peroxisomal Acyl-Coa Oxidase 1 - B Chain - Peroxisomal Acyl-Coa Oxidase 1 - C Chain |
| Database Links | Reactome: R-HSA-1989781 Q15067-1Reactome: R-HSA-2046106 Q15067-2Reactome: R-HSA-390247 Q15067-2Reactome: R-HSA-9033241Reactome: R-HSA-9033500 |
| Cellular Localisation | Peroxisome |
| Alternative Antibody Names | Anti-Peroxisomal Acyl-Coenzyme A Oxidase 1 antibodyAnti-Aox antibodyAnti-Palmitoyl-Coa Oxidase antibodyAnti-Peroxisomal Fatty Acyl-Coa Oxidase antibodyAnti-Straight-Chain Acyl-Coa Oxidase antibodyAnti-Scox Cleaved Into - Peroxisomal Acyl-Coa Oxidase 1 - A Chain - Peroxisomal Acyl-Coa Oxidase 1 - B Chain - Peroxisomal Acyl-Coa Oxidase 1 - C Chain antibodyAnti-ACOX1 antibodyAnti-ACOX antibody |
Information sourced from Uniprot.org