Anti-ACHE antibody (398-617) (STJ22484)

Name: Anti-ACHE antibody (398-617) (STJ22484)
SKU: STJ22484
Availability: InStock

⇓ Datasheet ⇓ SDS

SPECIFICATIONS

ClonalityPolyclonal

HostRabbit

ConjugationUnconjugated

IsotypeIgG

STJ22484

Current Stock:

🚚 Free UK Delivery on orders over £150

Quantity:

Processing The item has been added

Enquire For Bulk Order

✓ 1-Year Performance Guarantee | SDS & Datasheet Included | Expert Tech Support | Covered by St John's Laboratory Guarantee

Short Description	Rabbit polyclonal ACHE (398-617) antibody for use in WB, IF, ICC and ELISA in human, mouse and rat samples. Datasheet included with dilution recommendations, and related reagents.
Applications	WB/IF/ICC/ELISA
Host	Rabbit
Reactivity	Human/Mouse/Rat
Note	STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.

Clonality	Polyclonal
Isotype	IgG
Conjugation	Unconjugated
Concentration	Lot specific
Purification	Affinity purification
Dilution Range	WB:1:500-1:2000 IF/ICC:1:50-1:200 ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements.
Formulation	PBS with 0.02% Sodium Azide, 50% Glycerol, pH 7.3.
Storage Instruction	Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.

Gene Symbol	ACHE
Gene ID	43
Uniprot ID	ACES_HUMAN
Immunogen Region	398-617
Immunogen Sequence	VPQVSDLAAEAVVLHYTDWL HPEDPARLREALSDVVGDHN VVCPVAQLAGRLAAQGARVY AYVFEHRASTLSWPLWMGVP HGYEIEFIFGIPLDPSRNYT AEEKIFAQRLMRYWANFART GDPNEPRDPKAPQWPPYTAG AQQYVSLDLRPLEVRRGLRA QACAFWNRFLPKLLSATASE APSTCPGFTHGEAAPRPGLP LPLLLLHQLLLLFLSHLRRL
Specificity	Recombinant fusion protein containing a sequence corresponding to amino acids 398-617 of human ACHE (NP_056646.1).

Tissue Specificity	Isoform H is highly expressed in erythrocytes.
Function	Hydrolyzes rapidly the acetylcholine neurotransmitter released into the synaptic cleft allowing to terminate the signal transduction at the neuromuscular junction. Role in neuronal apoptosis.
Protein Name	Acetylcholinesterase Ache
Database Links	Reactome: R-HSA-112311 Reactome: R-HSA-1483191 Reactome: R-HSA-422085
Cellular Localisation	Synapse Secreted Cell Membrane Peripheral Membrane Protein Isoform T: Nucleus Only Observed In Apoptotic Nuclei Isoform H: Cell Membrane Lipid-Anchor Gpi-Anchor Extracellular Side
Alternative Antibody Names	Anti-Acetylcholinesterase antibody Anti-Ache antibody Anti-ACHE antibody

Information sourced from Uniprot.org