Anti-ACADS antibody (25-412aa) [AT8B10] (STJA0041832)
SPECIFICATIONS
ClonalityMonoclonal
HostMouse
ConjugationUnconjugated
IsotypeIgG2ak
ImmunogenRecombinant human ACADS (25-412aa) purified from E. coli
General Information
| Short Description | Mouse monoclonal anti-ACADS (25-412aa) for use in ELISA, WB, ICC and IF in Human samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | ELISA/WB/ICC/IF |
| Host | Mouse |
| Reactivity | Human |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Monoclonal |
| Clone ID | AT8B10 |
| Isotype | IgG2ak |
| Conjugation | Unconjugated |
| Concentration | 1 mg/mL |
| Purification | By protein-A affinity chromatography |
| Formulation | Liquid in phosphate-Buffered Saline (pH 7.4) with 0.02% Sodium Azide, 10% Glycerol |
| Storage Instruction | For short term storage, keep at +2C to +8C for up to 1 week. For long term storage, aliquot and store at-20C, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | ACADS |
| Gene ID | 35 |
| Uniprot ID | ACADS_HUMAN |
| Accession Number | AAH25963 |
| Immunogen | Recombinant human ACADS (25-412aa) purified from E. coli |
| Immunogen Region | 25-412aa |
Additional Info
| Function | Short-chain specific acyl-CoA dehydrogenase is one of the acyl-CoA dehydrogenases that catalyze the first step of mitochondrial fatty acid beta-oxidation, an aerobic process breaking down fatty acids into acetyl-CoA and allowing the production of energy from fats. The first step of fatty acid beta-oxidation consists in the removal of one hydrogen from C-2 and C-3 of the straight-chain fatty acyl-CoA thioester, resulting in the formation of trans-2-enoyl-CoA. Among the different mitochondrial acyl-CoA dehydrogenases, short-chain specific acyl-CoA dehydrogenase acts specifically on acyl-CoAs with saturated 4 to 6 carbons long primary chains. |
| Protein Name | Short-Chain Specific Acyl-Coa Dehydrogenase - MitochondrialScadButyryl-Coa Dehydrogenase |
| Database Links | Reactome: R-HSA-77350Reactome: R-HSA-77352 |
| Cellular Localisation | Mitochondrion Matrix |
| Alternative Antibody Names | Anti-Short-Chain Specific Acyl-Coa Dehydrogenase - Mitochondrial antibodyAnti-Scad antibodyAnti-Butyryl-Coa Dehydrogenase antibodyAnti-ACADS antibody |
Information sourced from Uniprot.org