| Host: | Rabbit |
| Applications: | WB |
| Reactivity: | Human/Mouse/Rat |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description : | Rabbit polyclonal anti-Long-chain specific acyl-CoA dehydrogenase, mitochondrial (258-308 aa) for use in WB in Human, Mouse and Rat samples. Datasheet included with dilution recommendations, and related reagents. |
| Clonality : | Polyclonal |
| Conjugation: | Unconjugated |
| Isotype: | IgG |
| Formulation: | Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide. |
| Purification: | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Concentration: | 1 mg/mL |
| Dilution Range: | WB 1:500-2000 |
| Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: | ACADL |
| Gene ID: | 33 |
| Uniprot ID: | ACADL_HUMAN |
| Immunogen Region: | 258-308 aa |
| Specificity: | This antibody detects endogenous levels of ACADL at Human/Mouse/Rat |
| Immunogen: | Synthesized peptide derived from the human ACADL at the amino acid range 258-308 |
| Function | Long-chain specific acyl-CoA dehydrogenase is one of the acyl-CoA dehydrogenases that catalyze the first step of mitochondrial fatty acid beta-oxidation, an aerobic process breaking down fatty acids into acetyl-CoA and allowing the production of energy from fats. The first step of fatty acid beta-oxidation consists in the removal of one hydrogen from C-2 and C-3 of the straight-chain fatty acyl-CoA thioester, resulting in the formation of trans-2-enoyl-CoA. Among the different mitochondrial acyl-CoA dehydrogenases, long-chain specific acyl-CoA dehydrogenase can act on saturated and unsaturated acyl-CoAs with 6 to 24 carbons with a preference for 8 to 18 carbons long primary chains. |
| Protein Name | Long-Chain Specific Acyl-Coa Dehydrogenase - MitochondrialLcad |
| Database Links | Reactome: R-HSA-77285Reactome: R-HSA-77288Reactome: R-HSA-77310 |
| Cellular Localisation | Mitochondrion Matrix |
| Alternative Antibody Names | Anti-Long-Chain Specific Acyl-Coa Dehydrogenase - Mitochondrial antibodyAnti-Lcad antibodyAnti-ACADL antibody |
Information sourced from Uniprot.org
