• Immunohistochemical analysis of paraffin-embedded Human ovary. Antibody was diluted at 1:100 (4°C overnight). High-pressure and temperature Tris-EDTA, pH8.0 was used for antigen retrieval. Negetive contrl (right) obtaned from antibody was pre-absorbed by immunogen peptide.
  • Western blot analysis of lysates from COLO cells, using ABHD12 Antibody. The lane on the right is blocked with the synthesized peptide.
  • Western blot analysis of various cells using ABHD12 Polyclonal Antibody

Anti-ABHD12 antibody (231-280 aa) (STJ91420)

SKU:
STJ91420

£46.00 - £226.00
Current Stock:
Host: Rabbit
Applications: WB/IHC/IF/ELISA
Reactivity: Human/Mouse/Rat
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description: Rabbit polyclonal antibody anti-Lysophosphatidylserine lipase ABHD12 (231-280 aa) is suitable for use in Western Blot, Immunohistochemistry, Immunofluorescence and ELISA research applications.
Clonality: Polyclonal
Conjugation: Unconjugated
Isotype: IgG
Formulation: Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide.
Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Concentration: 1 mg/mL
Dilution Range: WB 1:500-1:2000
IHC 1:100-1:300
ELISA 1:40000
IF 1:50-200
Storage Instruction: Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.
Gene Symbol: ABHD12
Gene ID: 26090
Uniprot ID: ABD12_HUMAN
Immunogen Region: 231-280 aa
Specificity: ABHD12 Polyclonal Antibody detects endogenous levels of ABHD12 protein.
Immunogen: The antiserum was produced against synthesized peptide derived from the human ABHD12 at the amino acid range 231-280
Function Lysophosphatidylserine (LPS) lipase that mediates the hydrolysis of lysophosphatidylserine, a class of signaling lipids that regulates immunological and neurological processes. Represents a major lysophosphatidylserine lipase in the brain, thereby playing a key role in the central nervous system. Also able to hydrolyze oxidized phosphatidylserine.oxidized phosphatidylserine is produced in response to severe inflammatory stress and constitutes a proapoptotic 'eat me' signal. Also has monoacylglycerol (MAG) lipase activity: hydrolyzes 2-arachidonoylglycerol (2-AG), thereby acting as a regulator of endocannabinoid signaling pathways. Has a strong preference for very-long-chain lipid substrates.substrate specificity is likely due to improved catalysis and not improved substrate binding.
Protein Name Lysophosphatidylserine Lipase Abhd12
2-Arachidonoylglycerol Hydrolase Abhd12
Abhydrolase Domain-Containing Protein 12
Habhd12
Monoacylglycerol Lipase Abhd12
Oxidized Phosphatidylserine Lipase Abhd12
Database Links Reactome: R-HSA-426048
Cellular Localisation Endoplasmic Reticulum Membrane
Single-Pass Membrane Protein
Alternative Antibody Names Anti-Lysophosphatidylserine Lipase Abhd12 antibody
Anti-2-Arachidonoylglycerol Hydrolase Abhd12 antibody
Anti-Abhydrolase Domain-Containing Protein 12 antibody
Anti-Habhd12 antibody
Anti-Monoacylglycerol Lipase Abhd12 antibody
Anti-Oxidized Phosphatidylserine Lipase Abhd12 antibody
Anti-ABHD12 antibody
Anti-C20orf22 antibody

Information sourced from Uniprot.org

12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance