| Host: | Rabbit |
| Applications: | WB/IHC-P/ICC/IF |
| Reactivity: | Human/Rat |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description : | Rabbit monoclonal anti-ABCF1 for use in WB, IHC-P, ICC and IF in Human and Rat samples. Datasheet included with dilution recommendations, and related reagents. |
| Clonality : | Monoclonal |
| Clone ID : | R07-8B7 |
| Conjugation: | Unconjugated |
| Isotype: | IgG |
| Formulation: | Rabbit IgG in phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
| Purification: | Affinity Chromatography |
| Dilution Range: | WB 1:500-1:1000IHC 1:50-1:100IF 1:50-1:200 |
| Storage Instruction: | Store at 4°C short term. Aliquot and store at-20°C long term. Avoid freeze/thaw cycles. |
| Gene Symbol: | ABCF1 |
| Gene ID: | 23 |
| Uniprot ID: | ABCF1_HUMAN |
| Immunogen: | A synthesized peptide derived from human ABCF1 |
| Tissue Specificity | Ubiquitous. |
| Post Translational Modifications | Isoform 2 is phosphorylated at phosphoserine and phosphothreonine. Isoform 2 phosphorylation on Ser-109 and Ser-140 by CK2 inhibits association of EIF2 with ribosomes. |
| Function | Isoform 2 is required for efficient Cap- and IRES-mediated mRNA translation initiation. Isoform 2 is not involved in the ribosome biogenesis. |
| Protein Name | Atp-Binding Cassette Sub-Family F Member 1Atp-Binding Cassette 50Tnf-Alpha-Stimulated Abc Protein |
| Database Links | Reactome: R-HSA-382556 |
| Cellular Localisation | Isoform 2: CytoplasmNucleusNucleoplasmNucleus Envelope |
| Alternative Antibody Names | Anti-Atp-Binding Cassette Sub-Family F Member 1 antibodyAnti-Atp-Binding Cassette 50 antibodyAnti-Tnf-Alpha-Stimulated Abc Protein antibodyAnti-ABCF1 antibodyAnti-ABC50 antibody |
Information sourced from Uniprot.org