Anti-ABCD4 antibody (111-160 aa) (STJ91415)
SPECIFICATIONS
ClonalityPolyclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
ImmunogenThe antiserum was produced against synthesized peptide derived from the human ABCD4 at the amino acid range 111-160
General Information
| Short Description | Rabbit polyclonal anti-Lysosomal cobalamin transporter ABCD4 (111-160 aa) for use in WB, IHC, IF and ELISA in Human and Mouse samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | WB/IHC/IF/ELISA |
| Host | Rabbit |
| Reactivity | Human/Mouse |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | 1 mg/mL |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Dilution Range | WB 1:500-1:2000IHC 1:100-1:300ELISA 1:10000IF 1:50-200 |
| Formulation | Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide. |
| Storage Instruction | Store at-20ยฐC for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | ABCD4 |
| Gene ID | 5826 |
| Uniprot ID | ABCD4_HUMAN |
| Immunogen | The antiserum was produced against synthesized peptide derived from the human ABCD4 at the amino acid range 111-160 |
| Immunogen Region | 111-160 aa |
| Specificity | ABCD4 Polyclonal Antibody detects endogenous levels of ABCD4 protein. |
Additional Info
| Function | Lysosomal membrane protein that transports cobalamin (Vitamin B12) from the lysosomal lumen to the cytosol in an ATP-dependent manner. Targeted by LMBRD1 lysosomal chaperone from the endoplasmic reticulum to the lysosomal membrane. Then forms a complex with lysosomal chaperone LMBRD1 and cytosolic MMACHC to transport cobalamin across the lysosomal membrane. |
| Protein Name | Lysosomal Cobalamin Transporter Abcd4Atp-Binding Cassette Sub-Family D Member 4Pmp70-Related ProteinP70rPeroxisomal Membrane Protein 1-LikePxmp1-LPeroxisomal Membrane Protein 69Pmp69 |
| Database Links | Reactome: R-HSA-5683329Reactome: R-HSA-9758881Reactome: R-HSA-9758890 |
| Cellular Localisation | Endoplasmic Reticulum MembraneMulti-Pass Membrane ProteinLysosome MembraneTargeted By Lmbrd1 Lysosomal Chaperone To The Lysosomal Membrane |
| Alternative Antibody Names | Anti-Lysosomal Cobalamin Transporter Abcd4 antibodyAnti-Atp-Binding Cassette Sub-Family D Member 4 antibodyAnti-Pmp70-Related Protein antibodyAnti-P70r antibodyAnti-Peroxisomal Membrane Protein 1-Like antibodyAnti-Pxmp1-L antibodyAnti-Peroxisomal Membrane Protein 69 antibodyAnti-Pmp69 antibodyAnti-ABCD4 antibodyAnti-PXMP1L antibody |
Information sourced from Uniprot.org