| Applications: | WB/IF/ICC/ELISA |
| Host: | Rabbit |
| Reactivity: | Human/Mouse/Rat |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Clonality : | Polyclonal |
| Isotype: | IgG |
| Conjugation: | Unconjugated |
| Concentration: | Lot specific |
| Purification: | Affinity purification |
| Dilution Range: | WB:1:500-1:1000IF/ICC:1:50-1:200ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Formulation: | PBS with 0.09% Sodium Azide, 50% Glycerol, pH 7.3. |
| Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: | ABAT |
| Gene ID: | 18 |
| Uniprot ID: | GABT_HUMAN |
| Immunogen Region: | 29-300 |
| Immunogen Sequence: | SQAAAKVDVEFDYDGPLMKT EVPGPRSQELMKQLNIIQNA EAVHFFCNYEESRGNYLVDV DGNRMLDLYSQISSVPIGYS HPALLKLIQQPQNASMFVNR PALGILPPENFVEKLRQSLL SVAPKGMSQLITMACGSCSN ENALKTIFMWYRSKERGQRG FSQEELETCMINQAPGCPDY SILSFMGAFHGRTMGCLATT HSKAIHKIDIPSFDWPIAPF PRLKYPLEEFVKENQQEEA |
| Specificity: | Recombinant fusion protein containing a sequence corresponding to amino acids 29-300 of human GABA transaminase (GABA transaminase (ABAT) ) (NP_001120920.1). |
| Tissue Specificity | Liver > pancreas > brain > kidney > heart > placenta. |
| Function | Catalyzes the conversion of gamma-aminobutyrate and L-beta-aminoisobutyrate to succinate semialdehyde and methylmalonate semialdehyde, respectively. Can also convert delta-aminovalerate and beta-alanine. |
| Protein Name | 4-Aminobutyrate Aminotransferase - Mitochondrial(S-3-Amino-2-Methylpropionate TransaminaseGaba AminotransferaseGaba-AtGamma-Amino-N-Butyrate TransaminaseGaba TransaminaseGaba-TL-Aibat |
| Database Links | Reactome: R-HSA-916853 |
| Cellular Localisation | Mitochondrion Matrix |
| Alternative Antibody Names | Anti-4-Aminobutyrate Aminotransferase - Mitochondrial antibodyAnti-(S-3-Amino-2-Methylpropionate Transaminase antibodyAnti-Gaba Aminotransferase antibodyAnti-Gaba-At antibodyAnti-Gamma-Amino-N-Butyrate Transaminase antibodyAnti-Gaba Transaminase antibodyAnti-Gaba-T antibodyAnti-L-Aibat antibodyAnti-ABAT antibodyAnti-GABAT antibody |
Information sourced from Uniprot.org
