| Host: | Goat |
| Applications: | Pep-ELISA/WB |
| Reactivity: | Human/Dog/Cow |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description : | Goat polyclonal antibody anti-A4GNT/alpha4GNT (C-Term) is suitable for use in ELISA and Western Blot research applications. |
| Clonality : | Polyclonal |
| Conjugation: | Unconjugated |
| Isotype: | IgG |
| Formulation: | 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin. NA |
| Purification: | Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide. |
| Concentration: | 0.5 mg/mL |
| Dilution Range: | Peptide ELISA: antibody detection limit dilution 1:8000.WB: Approx 40kDa band observed in lysates of cell line K562 (calculated MW of 39.5kDa according to NP_057245.1). Recommended concentration: 1-3µg/ml. |
| Storage Instruction: | Store at-20°C on receipt and minimise freeze-thaw cycles. |
| Gene Symbol: | A4GNT |
| Gene ID: | 51146 |
| Uniprot ID: | A4GCT_HUMAN |
| Immunogen Region: | C-Term |
| Accession Number: | NP_057245.1 |
| Immunogen Sequence: | PRTYRDLIKGPEGS |
| Function | Catalyzes the transfer of N-acetylglucosamine (GlcNAc) to core 2 branched O-glycans. Necessary for the synthesis of type III mucin which is specifically produced in the stomach, duodenum, and pancreatic duct. May protect against inflammation-associated gastric adenocarcinomas. |
| Protein Name | Alpha-1 -4-N-AcetylglucosaminyltransferaseAlpha4gnt |
| Database Links | Reactome: R-HSA-913709 |
| Cellular Localisation | Golgi Apparatus MembraneSingle-Pass Type Ii Membrane Protein |
| Alternative Antibody Names | Anti-Alpha-1 -4-N-Acetylglucosaminyltransferase antibodyAnti-Alpha4gnt antibodyAnti-A4GNT antibody |
Information sourced from Uniprot.org