| Host: |
Rabbit |
| Applications: |
IHC/WB |
| Reactivity: |
Human/Marmoset/Rat/Mouse |
| Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description: |
Rabbit polyclonal antibody anti-5HT1D R (C-Term) is suitable for use in Immunohistochemistry and Western Blot research applications. |
| Clonality: |
Polyclonal |
| Conjugation: |
Unconjugated |
| Isotype: |
IgG |
| Formulation: |
Lyophilised |
| Purification: |
IgG purified |
| Dilution Range: |
IHC, WB. A dilution of 1: 1000 is recommended. The optimal dilution should be determined by the end user. Not yet tested in other applications. |
| Storage Instruction: |
Maintain the lyophilised/reconstituted antibodies frozen at-20°C for long term storage and refrigerated at 2-8°C for a shorter term. When reconstituting, Glycerol (1:1) may be added for an additional stability. Avoid freeze and thaw cycles. |
| Gene Symbol: |
HTR1D |
| Gene ID: |
3352 |
| Uniprot ID: |
5HT1D_HUMAN |
| Immunogen Region: |
C-Term |
| Specificity: |
Specific for 5HT1D receptor. |
| Immunogen: |
A synthetic peptide from c-terminal region of human 5HT1D receptor conjugated to blue carrier protein was used as the antigen. |
| Function | G-protein coupled receptor for 5-hydroxytryptamine (serotonin). Also functions as a receptor for ergot alkaloid derivatives, various anxiolytic and antidepressant drugs and other psychoactive substances. Ligand binding causes a conformation change that triggers signaling via guanine nucleotide-binding proteins (G proteins) and modulates the activity of downstream effectors, such as adenylate cyclase. HTR1D is coupled to G(i)/G(o) G alpha proteins and mediates inhibitory neurotransmission by inhibiting adenylate cyclase activity. Regulates the release of 5-hydroxytryptamine in the brain, and thereby affects neural activity. May also play a role in regulating the release of other neurotransmitters. May play a role in vasoconstriction. |
| Protein Name | 5-Hydroxytryptamine Receptor 1d5-Ht-1d5-Ht1dSerotonin 1d Alpha Receptor5-Ht-1d-AlphaSerotonin Receptor 1d |
| Database Links | Reactome: R-HSA-390666Reactome: R-HSA-418594 |
| Cellular Localisation | Cell MembraneMulti-Pass Membrane Protein |
| Alternative Antibody Names | Anti-5-Hydroxytryptamine Receptor 1d antibodyAnti-5-Ht-1d antibodyAnti-5-Ht1d antibodyAnti-Serotonin 1d Alpha Receptor antibodyAnti-5-Ht-1d-Alpha antibodyAnti-Serotonin Receptor 1d antibodyAnti-HTR1D antibodyAnti-HTR1DA antibodyAnti-HTRL antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
