Anti-TNFSF9 antibody (155-254) [S9MR] (STJ11101859)
SPECIFICATIONS
ClonalityMonoclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
General Information
| Short Description | Rabbit monoclonal 4-1BBL/CD137L (155-254) antibody for use in WB and ELISA in human, mouse and rat samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | WB/ELISA |
| Host | Rabbit |
| Reactivity | Human/Mouse/Rat |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Monoclonal |
| Clone ID | S9MR |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | Lot specific |
| Purification | Affinity purification |
| Dilution Range | WB:1:1000-1:4000ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Formulation | PBS with 0.02% Sodium Azide, 0.05% BSA, 50% Glycerol, pH 7.3. |
| Storage Instruction | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | TNFSF9 |
| Gene ID | 8744 |
| Uniprot ID | TNFL9_HUMAN |
| Immunogen Region | 155-254 |
| Immunogen Sequence | GEGSGSVSLALHLQPLRSAA GAAALALTVDLPPASSEARN SAFGFQGRLLHLSAGQRLGV HLHTEARARHAWQLTQGATV LGLFRVTPEIPAGLPSPRSE |
| Specificity | A synthetic peptide corresponding to a sequence within amino acids 155-254 of human 4-1BBL/CD137L (P41273). |
Additional Info
| Tissue Specificity | Expressed in brain, placenta, lung, skeletal muscle and kidney. |
| Function | Cytokine that binds to TNFRSF9. Induces the proliferation of activated peripheral blood T-cells. May have a role in activation-induced cell death (AICD). May play a role in cognate interactions between T-cells and B-cells/macrophages. |
| Protein Name | Tumor Necrosis Factor Ligand Superfamily Member 94-1bb Ligand4-1bbl |
| Database Links | Reactome: R-HSA-5669034 |
| Cellular Localisation | MembraneSingle-Pass Type Ii Membrane Protein |
| Alternative Antibody Names | Anti-Tumor Necrosis Factor Ligand Superfamily Member 9 antibodyAnti-4-1bb Ligand antibodyAnti-4-1bbl antibodyAnti-TNFSF9 antibody |
Information sourced from Uniprot.org