| Host: | Rabbit |
| Applications: | WB/ELISA |
| Reactivity: | Human |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Clonality : | Polyclonal |
| Conjugation: | Unconjugated |
| Isotype: | IgG |
| Formulation: | PBS with 0.02% Sodium Azide, 50% Glycerol, pH 7.3. |
| Purification: | Affinity purification |
| Concentration: | Lot specific |
| Dilution Range: | WB:1:500-1:2000ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Gene Symbol: | TNFSF9 |
| Gene ID: | 8744 |
| Uniprot ID: | TNFL9_HUMAN |
| Immunogen Region: | 55-254 aa |
| Specificity: | Recombinant fusion protein containing a sequence corresponding to amino acids 55-254 of human 4-1BBL/CD137L (NP_003802.1). |
| Immunogen Sequence: | VSGARASPGSAASPRLREGP ELSPDDPAGLLDLRQGMFAQ LVAQNVLLIDGPLSWYSDPG LAGVSLTGGLSYKEDTKELV VAKAGVYYVFFQLELRRVVA GEGSGSVSLALHLQPLRSAA GAAALALTVDLPPASSEARN SAFGFQGRLLHLSAGQRLGV HLHTEARARHAWQLTQGATV LGLFRVTPEIPAGLPSPRSE |
| Tissue Specificity | Expressed in brain, placenta, lung, skeletal muscle and kidney. |
| Function | Cytokine that binds to TNFRSF9. Induces the proliferation of activated peripheral blood T-cells. May have a role in activation-induced cell death (AICD). May play a role in cognate interactions between T-cells and B-cells/macrophages. |
| Protein Name | Tumor Necrosis Factor Ligand Superfamily Member 94-1bb Ligand4-1bbl |
| Database Links | Reactome: R-HSA-5669034 |
| Cellular Localisation | MembraneSingle-Pass Type Ii Membrane Protein |
| Alternative Antibody Names | Anti-Tumor Necrosis Factor Ligand Superfamily Member 9 antibodyAnti-4-1bb Ligand antibodyAnti-4-1bbl antibodyAnti-TNFSF9 antibody |
Information sourced from Uniprot.org