Animal Free Human IL-21 protein (Recombinant) (No-Tag) (STJP019426)

SKU:
STJP019426
€270.60 - €1,740.60
Free Shipping
Processing The item has been added
Enquire For Bulk Order

Covered by St John's Laboratory Guarantee

Host: E.coli
Applications: SDS-PAGE/Bioactivity
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description : Recombinant-Animal Free Human IL-21-No-Tag protein was developed from e.coli and has a target region of No-Tag. For use in research applications.
Formulation: Liquid in phosphate-Buffered Saline (pH 7.4)
Concentration: 0.25 mg/mL
Storage Instruction: For short term storage, keep at +2C to +8C for up to 1 week. For long term storage, aliquot and store at-20C, and avoid repeat freeze-thaw cycles.
Endotoxin: < 1 EU per 1ug of protein (determined by LAL method)
Immunoreactivity: The activity is determined by the IFN-Gamma ELISA in a using NK-92 human natural killer cells. The ED50 range ≤ 4 ng/ml.
Gene Symbol: IL21
Gene ID: 59067
Uniprot ID: IL21_HUMAN
Immunogen Region: 30-162aa
Accession Number: NP_068575
Immunogen Sequence: MQGQDRHMIR MRQLIDIVDQ LKNYVNDLVP EFLPAPEDVE TNCEWSAFSC FQKAQLKSAN GNNERIINV SIKKLKRKPP STNAGRRQKH RLTCPSCDSY EKKPPKEFLE RFKSLLQKMI HQHLSSRTHG SEDS
Tissue Specificity Expressed in activated CD4-positive T-cells but not in CD8-positive T-cells, B-cells, or monocytes.
Function Cytokine with immunoregulatory activity. May promote the transition between innate and adaptive immunity. Induces the production of IgG(1) and IgG(3) in B-cells. Implicated in the generation and maintenance of T follicular helper (Tfh) cells and the formation of germinal-centers. Together with IL6, control the early generation of Tfh cells and are critical for an effective antibody response to acute viral infection. May play a role in proliferation and maturation of natural killer (NK) cells in synergy with IL15. May regulate proliferation of mature B- and T-cells in response to activating stimuli. In synergy with IL15 and IL18 stimulates interferon gamma production in T-cells and NK cells. During T-cell mediated immune response may inhibit dendritic cells (DC) activation and maturation.
Protein Name Interleukin-21
Il-21
Za11
Database Links Reactome: R-HSA-9020958
Cellular Localisation Secreted
Alternative Protein Names Interleukin-21 protein
Il-21 protein
Za11 protein
IL21 protein

Information sourced from Uniprot.org

Related Products

Model Name Host Clonality Reactivity Application
STJP020081 Human IL-21 protein (Recombinant) (No-tag) (STJP020081) HEK293 cells
STJP019409 Human IL-21 protein (Recombinant) (No-Tag) (STJP019409) E.coli SDS-PAGE/Bioactivity
STJP019563 Animal Free Human EGF protein (Recombinant) (No-Tag) (STJP019563) E.coli SDS-PAGE/Bioactivity
STJP012765 Human IL36RN/IL-1F5/IL-36Ra protein (Recombinant-Active) (Tag free) (STJP012765) E.coli ELISA/WB
STJP012757 Human IL36B/IL-1F8 protein (Recombinant-Active) (Tag free) (STJP012757) E.coli ELISA/WB

Related Products

!