| Applications: | WB |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description : | ADCY5 Positive Control for STJ502071 is synthetically produced from the sequence and is suitable for use in western blot applications. |
| Formulation: | Provided as 100 uL ready-to-use, in SDS-PAGE sample buffer (Laemelli's buffer) containing Tris, pH 6.8, 1 % SDS, Glycerol and Bromophenolblue blue as tracking dye. The sample is reduced by adding 2% beta mercaptoethanol. The protein concentration is |
| Storage Instruction: | Store at-20°C for long term storage. Avoid freeze-thaw cycles. |
| Gene Symbol: | Adcy5 |
| Gene ID: | 64532 |
| Uniprot ID: | ADCY5_RAT |
| Specificity: | This is positive control is recommended for use in combination with ADCY5 antibody STJ502071. |
| Tissue Specificity | Detected in brain and kidney. |
| Post Translational Modifications | Phosphorylated by RAF1. |
| Function | Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. Mediates signaling downstream of ADRB1. Regulates the increase of free cytosolic Ca(2+) in response to increased blood glucose levels and contributes to the regulation of Ca(2+)-dependent insulin secretion. |
| Peptide Name | Adenylate Cyclase Type 5Atp Pyrophosphate-Lyase 5Adenylate Cyclase Type VAdenylyl Cyclase 5 |
| Database Links | Reactome: R-RNO-163615Reactome: -RNO-170660Reactome: -RNO-170670Reactome: -RNO-400042Reactome: -RNO-418597Reactome: -RNO-5610787 |
| Cellular Localisation | Cell MembraneMulti-Pass Membrane ProteinCell ProjectionCilium |
| Alternative Peptide Names | Adenylate Cyclase Type 5 proteinAtp Pyrophosphate-Lyase 5 proteinAdenylate Cyclase Type V proteinAdenylyl Cyclase 5 proteinAdcy5 protein |
Information sourced from Uniprot.org