| Applications: | WB |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description : | ADCY2 Positive Control for STJ502054 is synthetically produced from the sequence and is suitable for use in western blot applications. |
| Formulation: | Provided as 100 uL ready-to-use, in SDS-PAGE sample buffer (Laemelli's buffer) containing Tris, pH 6.8, 1 % SDS, Glycerol and Bromophenolblue blue as tracking dye. The sample is reduced by adding 2% beta mercaptoethanol. The protein concentration is |
| Storage Instruction: | Store at-20°C for long term storage. Avoid freeze-thaw cycles. |
| Gene Symbol: | Adcy2 |
| Gene ID: | 81636 |
| Uniprot ID: | ADCY2_RAT |
| Specificity: | This is positive control is recommended for use in combination with ADCY2 antibody STJ502054. |
| Tissue Specificity | Expressed in brain, olfactory epithelium and lung. |
| Post Translational Modifications | Phosphorylated by RAF1. |
| Function | Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. Down-stream signaling cascades mediate changes in gene expression patterns and lead to increased IL6 production. Functions in signaling cascades downstream of the muscarinic acetylcholine receptors. |
| Peptide Name | Adenylate Cyclase Type 2 Atp Pyrophosphate-Lyase 2 Adenylate Cyclase Type Ii Adenylyl Cyclase 2 Ac2 |
| Database Links | Reactome: R-RNO-163615 Reactome: -RNO-170660 Reactome: -RNO-170670 Reactome: -RNO-418597 Reactome: -RNO-5610787 |
| Cellular Localisation | Membrane Multi-Pass Membrane Protein Cell Membrane Cytoplasm |
| Alternative Peptide Names | Adenylate Cyclase Type 2 protein Atp Pyrophosphate-Lyase 2 protein Adenylate Cyclase Type Ii protein Adenylyl Cyclase 2 protein Ac2 protein Adcy2 protein |
Information sourced from Uniprot.org