Mouse CD120a/TNFRSF1A/TNFR1 protein (Recombinant) (C-Fc) (STJP008682)

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STJP008682
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Host: Mammalian Cells
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description : Recombinant-Mouse CD120a/TNFRSF1A/TNFR1-C-Fc protein was developed from mammalian cells and has a target region of C-Fc. For use in research applications.
Formulation: Lyophilized from a solution in PBS pH 7.4, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Storage Instruction: Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at-20 to-80°C for twelve months from the date of receipt.
Gene Symbol: Tnfrsf1a
Gene ID: 21937
Uniprot ID: TNR1A_MOUSE
Immunogen Region: Met1-Ala212
Immunogen: Mus musculus (Mouse)
Function Receptor for TNFSF2/TNF-alpha and homotrimeric TNFSF1/lymphotoxin-alpha. The adapter molecule FADD recruits caspase-8 to the activated receptor. The resulting death-inducing signaling complex (DISC) performs caspase-8 proteolytic activation which initiates the subsequent cascade of caspases (aspartate-specific cysteine proteases) mediating apoptosis.
Protein Name Tumor Necrosis Factor Receptor Superfamily Member 1a
Tumor Necrosis Factor Receptor 1
Tnf-R1
Tumor Necrosis Factor Receptor Type I
Tnf-Ri
Tnfr-I
P55
P60
Cd Antigen Cd120a
Database Links Reactome: R-MMU-5357786
Reactome: -MMU-5357905
Reactome: -MMU-5357956
Reactome: -MMU-5626978
Reactome: -MMU-5669034
Reactome: -MMU-75893
Cellular Localisation Cell Membrane
Single-Pass Type I Membrane Protein
Golgi Apparatus Membrane
Alternative Protein Names Tumor Necrosis Factor Receptor Superfamily Member 1a protein
Tumor Necrosis Factor Receptor 1 protein
Tnf-R1 protein
Tumor Necrosis Factor Receptor Type I protein
Tnf-Ri protein
Tnfr-I protein
P55 protein
P60 protein
Cd Antigen Cd120a protein
Tnfrsf1a protein
Tnfr-1 protein
Tnfr1 protein

Information sourced from Uniprot.org

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