| Host: |
HEK293 cells |
| Reactivity: |
Human |
| Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description: |
Recombinant-Human RRM2-C-His protein was developed from hek293 cells and has a target region of C-His. For use in research applications. |
| Formulation: |
Lyophilized from a 0.22 Mu m filtered solution of 20mM Tris-HCl, 150mM NaCl, 5% Trehalose, pH 8.0. |
| Storage Instruction: |
Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: |
RRM2 |
| Gene ID: |
6241 |
| Uniprot ID: |
RIR2_HUMAN |
| Immunogen Region: |
Met1-Phe389 |
| Immunogen: |
Recombinant Human RRM2 Protein is produced by HEK293 cells expression system. The target protein is expressed with sequence (Met1-Phe389) of Human RRM2 (Accession #NP_001025.1) fused with a 6×His tag at the C-terminus. |
| Function | Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides. Inhibits Wnt signaling. |
| Protein Name | Ribonucleoside-Diphosphate Reductase Subunit M2Ribonucleotide Reductase Small ChainRibonucleotide Reductase Small Subunit |
| Database Links | Reactome: R-HSA-499943Reactome: R-HSA-69205Reactome: R-HSA-8953750 |
| Cellular Localisation | CytoplasmNucleusLocalized To The Cytoplasm In S Phase CellsMay Localize To The Nucleus In G2 Phase Cells |
| Alternative Protein Names | Ribonucleoside-Diphosphate Reductase Subunit M2 proteinRibonucleotide Reductase Small Chain proteinRibonucleotide Reductase Small Subunit proteinRRM2 proteinRR2 protein |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
