Human NKp30/NCR3 (Natural cytotoxicity triggering receptor 3) Sandwich ELISA Kit (STJE0020119)

SKU:
STJE0020119-96
$600.08
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Applications: ELISA
Reactivity: Human
Note: FOR SCIENTIFIC EDUCATIONAL RESEARCH USE ONLY (RUO). MUST NOT BE USED IN DIAGNOSTIC OR OTHER MEDICAL APPLICATIONS.
Sensitivity: 9.375 pg/mL
Detection Limit: 15.625-1000 pg/mL
Storage Instruction: Store unopened box at 2-8 °C for up to 1 month. For longer storage check individual components.
Assay Time: 4 hours
Gene Symbol: NCR3
Gene ID: 259197
Uniprot ID: NCTR3_HUMAN
Specificity: This Sandwich ELISA kit recognizes Human Natural cytotoxicity triggering receptor 3 in various sample types. No significant cross-reactivity or interference was observed between Human NKp30/NCR3 analogues.
Sample Type: Serum, Plasma, Cell Culture Supernatant, cell or tissue lysate, Other liquid samples
Tissue Specificity Selectively expressed by all resting and activated NK cells and weakly expressed in spleen.
Post Translational Modifications
Function Cell membrane receptor of natural killer/NK cells that is activated by binding of extracellular ligands including BAG6 and NCR3LG1. Stimulates NK cells cytotoxicity toward neighboring cells producing these ligands. It controls, for instance, NK cells cytotoxicity against tumor cells. Engagement of NCR3 by BAG6 also promotes myeloid dendritic cells (DC) maturation, both through killing DCs that did not acquire a mature phenotype, and inducing the release by NK cells of TNFA and IFNG which promote DC maturation.
Protein Name Natural Cytotoxicity Triggering Receptor 3
Activating Natural Killer Receptor P30
Natural Killer Cell P30-Related Protein
Nk-P30
Nkp30
Cd Antigen Cd337
Database Links Reactome: R-HSA-198933
Cellular Localisation Cell Membrane
Single-Pass Type I Membrane Protein
Alternative ELISA Names Natural Cytotoxicity Triggering Receptor 3 ELISA kit
Activating Natural Killer Receptor P30 ELISA kit
Natural Killer Cell P30-Related Protein ELISA kit
Nk-P30 ELISA kit
Nkp30 ELISA kit
Cd Antigen Cd337 ELISA kit
NCR3 ELISA kit
1C7 ELISA kit
LY117 ELISA kit
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Information sourced from Uniprot.org