Human IL-1R2 (Interleukin-1 Receptor Type 2) Antibody Pair (STJAP00379)

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STJAP00379-50
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Host: Rabbit/Mouse
Applications: ELISA
Reactivity: Human
Note: FOR SCIENTIFIC EDUCATIONAL RESEARCH USE ONLY (RUO). MUST NOT BE USED IN DIAGNOSTIC OR OTHER MEDICAL APPLICATIONS.
Short Description : This IL-1R2 antibody pair contains complimentary capture and detection antibodies, which work together under the principals of the Sandwich ELISA.
Conjugation: Unconjugated/Biotin
Formulation: Capture Buffer: PBS with 0.04% Proclin 300; 50% glycerol; pH 7.5.
Detection Buffer: PBS with 0.04% Proclin 300; 1% protective protein; 50% glycerol; pH 7.5.
Purification: Capture Purification: Protein A or G.
Detection Purification: Protein A or G.
Concentration: 0.5 mg/mL
Storage Instruction: Store at-20°C for long term, and avoid freeze-thaw cycles.
Determination Method: Colormetric
Gene Symbol: IL1R2
Gene ID: 7850
Uniprot ID: IL1R2_HUMAN
Immunogen: Capture immunogen: Recombinant Human IL-1R2 protien.
Detection Immunogen: Recombinant Human IL-1R2 protien.
Sample Type: Serum, plasma and other biological fluids
Function Non-signaling receptor for IL1A, IL1B and IL1RN. Reduces IL1B activities. Serves as a decoy receptor by competitive binding to IL1B and preventing its binding to IL1R1. Also modulates cellular response through non-signaling association with IL1RAP after binding to IL1B. IL1R2 (membrane and secreted forms) preferentially binds IL1B and poorly IL1A and IL1RN. The secreted IL1R2 recruits secreted IL1RAP with high affinity.this complex formation may be the dominant mechanism for neutralization of IL1B by secreted/soluble receptors.
Protein Name Interleukin-1 Receptor Type 2
Il-1r-2
Il-1rt-2
Il-1rt2
Cd121 Antigen-Like Family Member B
Cdw121b
Il-1 Type Ii Receptor
Interleukin-1 Receptor Beta
Il-1r-Beta
Interleukin-1 Receptor Type Ii
Cd Antigen Cd121b Cleaved Into - Interleukin-1 Receptor Type 2 - Membrane Form
Mil-1r2
Mil-1rii - Interleukin-1 Receptor Type 2 - Soluble Form
Sil-1r2
Sil-1rii
Database Links Reactome: R-HSA-6783783
Reactome: R-HSA-9020702
Cellular Localisation Isoform Short: Secreted
Isoform Long: Cell Membrane
Single-Pass Type I Membrane Protein
Alternative Antibody Pair Names Interleukin-1 Receptor Type 2 antibody pair
Il-1r-2 antibody pair
Il-1rt-2 antibody pair
Il-1rt2 antibody pair
Cd121 Antigen-Like Family Member B antibody pair
Cdw121b antibody pair
Il-1 Type Ii Receptor antibody pair
Interleukin-1 Receptor Beta antibody pair
Il-1r-Beta antibody pair
Interleukin-1 Receptor Type Ii antibody pair
Cd Antigen Cd121b Cleaved Into - Interleukin-1 Receptor Type 2 - Membrane Form antibody pair
Mil-1r2 antibody pair
Mil-1rii - Interleukin-1 Receptor Type 2 - Soluble Form antibody pair
Sil-1r2 antibody pair
Sil-1rii antibody pair
IL1R2 antibody pair
IL1RB antibody pair

Information sourced from Uniprot.org

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