Human CXCL17/DMC/VCC1 protein (Recombinant) (N-GST) (STJP005602)

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STJP005602
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Host: E. coli
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description : Recombinant-Human CXCL17/DMC/VCC1-N-GST protein was developed from e. coli and has a target region of N-GST. For use in research applications.
Formulation: Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Storage Instruction: Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at-20 to-80°C for twelve months from the date of receipt.
Gene Symbol: CXCL17
Gene ID: 284340
Uniprot ID: CXL17_HUMAN
Immunogen Region: Leu24-Leu119
Immunogen: Homo sapiens (Human)
Post Translational Modifications Likely to undergo an endoproteolytic process to form a four-cysteine-containing mature peptide with a canonical CXC chemokine scaffold after secretion.
Function Chemokine that acts as a chemoattractant for monocytes, macrophages and dendritic cells. Plays a role in angiogenesis and possibly in the development of tumors. Acts as an anti-inflammatory in the stomach. May play a role in the innate defense against infections. Activates the C-X-C chemokine receptor GPR35 to induce a rapid and transient rise in the level of intracellular calcium ions. 4-Cys CXCL17: Seems to exhibit much higher chemoattractant potency on monocytes and macrophages than 6-Cys CXCL17.
Protein Name C-X-C Motif Chemokine 17
6-Cys Cxcl17
Dendritic Cell And Monocyte Chemokine-Like Protein
Dmc
Vegf Coregulated Chemokine 1 Cleaved Into - 4-Cys Cxcl17
Cellular Localisation Secreted
Alternative Protein Names C-X-C Motif Chemokine 17 protein
6-Cys Cxcl17 protein
Dendritic Cell And Monocyte Chemokine-Like Protein protein
Dmc protein
Vegf Coregulated Chemokine 1 Cleaved Into - 4-Cys Cxcl17 protein
CXCL17 protein
VCC1 protein
UNQ473 protein
PRO842 protein

Information sourced from Uniprot.org

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