| Host: |
Rabbit |
| Applications: |
WB/IHC |
| Reactivity: |
Mouse/Rat |
| Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description: |
Rabbit polyclonal antibody anti-WRB (30-100) is suitable for use in Western Blot and Immunohistochemistry research applications. |
| Clonality: |
Polyclonal |
| Conjugation: |
Unconjugated |
| Isotype: |
IgG |
| Formulation: |
PBS with 0.02% Sodium Azide, 50% Glycerol, pH7.3. |
| Purification: |
Affinity purification |
| Dilution Range: |
WB 1:500-1:2000IHC-P 1:50-1:200 |
| Storage Instruction: |
Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: |
GET1 |
| Gene ID: |
7485 |
| Uniprot ID: |
GET1_HUMAN |
| Immunogen Region: |
30-100 |
| Immunogen: |
Recombinant fusion protein containing a sequence corresponding to amino acids 30-100 of human WRB (NP_004618.2). |
| Immunogen Sequence: |
SFSSFMSRVLQKDAEQESQM RAEIQDMKQELSTVNMMDEF ARYARLERKINKMTDKLKTH VKARTAQLAKI |
| Function | Required for the post-translational delivery of tail-anchored (TA) proteins to the endoplasmic reticulum (ER). Together with CAMLG/GET2, acts as a membrane receptor for soluble GET3/TRC40, which recognizes and selectively binds the transmembrane domain of TA proteins in the cytosol. Required to ensure correct topology and ER insertion of CAMLG. |
| Protein Name | Guided Entry Of Tail-Anchored Proteins Factor 1Congenital Heart Disease 5 ProteinTail-Anchored Protein Insertion Receptor WrbTryptophan-Rich Basic Protein |
| Database Links | Reactome: R-HSA-9609523 |
| Cellular Localisation | Endoplasmic Reticulum MembraneMulti-Pass Membrane Protein |
| Alternative Antibody Names | Anti-Guided Entry Of Tail-Anchored Proteins Factor 1 antibodyAnti-Congenital Heart Disease 5 Protein antibodyAnti-Tail-Anchored Protein Insertion Receptor Wrb antibodyAnti-Tryptophan-Rich Basic Protein antibodyAnti-GET1 antibodyAnti-CHD5 antibodyAnti-WRB antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
