| Host: |
Rabbit |
| Applications: |
WB/ELISA |
| Reactivity: |
Human/Rat |
| Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Clonality: |
Polyclonal |
| Conjugation: |
Unconjugated |
| Isotype: |
IgG |
| Formulation: |
PBS with 0.01% Thimerosal, 50% Glycerol, pH 7.3. |
| Purification: |
Affinity purification |
| Concentration: |
Lot specific |
| Dilution Range: |
WB:1:500-1:2000ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Storage Instruction: |
Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: |
TMEM126A |
| Gene ID: |
84233 |
| Uniprot ID: |
T126A_HUMAN |
| Immunogen Region: |
1-195 |
| Specificity: |
Recombinant fusion protein containing a sequence corresponding to amino acids 1-195 of human TMEM126A (NP_115649.1). |
| Immunogen Sequence: |
MENHKSNNKENITIVDISRK INQLPEAERNLLENGSVYVG LNAALCGLIANSLFRRILNV TKARIAAGLPMAGIPFLTTD LTYRCFVSFPLNTGDLDCET CTITRSGLTGLVIGGLYPVF LAIPVNGGLAARYQSALLPH KGNILSYWIRTSKPVFRKML FPILLQTMFSAYLGSEQYKL LIKALQLSEPGKEIH |
| Tissue Specificity | Strongly expressed in brain, cerebellum, skeletal muscle, testis. High expression also found in fetal brain, fetal retinal pigmentary epithelium, and fetal retina. Highly expressed in retinal ganglion cells. |
| Function | Protein required for the cotranslational protein quality control in the inner membrane of the mitochondria. Associates with newly synthesized polypeptides and may act as a chaperone that cooperates with OXA1L for the insertion of newly synthesized mitochondrial proteins into the inner membrane. Required for the assembly of the ND4 module of mitochondrial complex I. |
| Protein Name | Transmembrane Protein 126a |
| Database Links | Reactome: R-HSA-6799198 |
| Cellular Localisation | Mitochondrion Inner MembraneMulti-Pass Membrane Protein |
| Alternative Antibody Names | Anti-Transmembrane Protein 126a antibodyAnti-TMEM126A antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
