| Host: |
Rabbit |
| Applications: |
WB |
| Reactivity: |
Human/Mouse |
| Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description: |
Rabbit polyclonal antibody anti-TMED1 (24-194) is suitable for use in Western Blot research applications. |
| Clonality: |
Polyclonal |
| Conjugation: |
Unconjugated |
| Isotype: |
IgG |
| Formulation: |
PBS with 0.02% Sodium Azide, 50% Glycerol, pH7.3. |
| Purification: |
Affinity purification |
| Dilution Range: |
WB 1:500-1:2000 |
| Storage Instruction: |
Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: |
TMED1 |
| Gene ID: |
11018 |
| Uniprot ID: |
TMED1_HUMAN |
| Immunogen Region: |
24-194 |
| Immunogen: |
Recombinant fusion protein containing a sequence corresponding to amino acids 24-194 of human TMED1 (NP_006849.1). |
| Immunogen Sequence: |
AGPPPIQDGEFTFLLPAGRK QCFYQSAPANASLETEYQVI GGAGLDVDFTLESPQGVLLV SESRKADGVHTVEPTEAGDY KLCFDNSFSTISEKLVFFEL IFDSLQDDEEVEGWAEAVEP EEMLDVKMEDIKESIETMRT RLERSIQMLTLLRAFEARDR NLQEGNLERVN |
| Tissue Specificity | Widely expressed. |
| Function | Potential role in vesicular protein trafficking, mainly in the early secretory pathway. May act as a cargo receptor at the lumenal side for incorporation of secretory cargo molecules into transport vesicles and may be involved in vesicle coat formation at the cytoplasmic side. Plays a positive role in IL-33-mediated IL-8 and IL-6 production by interacting with interleukin-33 receptor IL1RL1. Also plays a role in the modulation of innate immune signaling through the cGAS-STING pathway by interacting with RNF26. |
| Protein Name | Transmembrane Emp24 Domain-Containing Protein 1Interleukin-1 Receptor-Like 1 LigandPutative T1/St2 Receptor-Binding ProteinP24 Family Protein Gamma-1Tp24P24gamma1 |
| Cellular Localisation | Cell MembraneSingle-Pass Type I Membrane ProteinEndoplasmic Reticulum MembraneGolgi ApparatusCis-Golgi Network MembraneEndoplasmic Reticulum-Golgi Intermediate Compartment Membrane |
| Alternative Antibody Names | Anti-Transmembrane Emp24 Domain-Containing Protein 1 antibodyAnti-Interleukin-1 Receptor-Like 1 Ligand antibodyAnti-Putative T1/St2 Receptor-Binding Protein antibodyAnti-P24 Family Protein Gamma-1 antibodyAnti-Tp24 antibodyAnti-P24gamma1 antibodyAnti-TMED1 antibodyAnti-IL1RL1L antibodyAnti-IL1RL1LG antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
