Tissue Specificity | Ubiquitous, with highest expression in heart, kidney, liver and skeletal muscle. |
Function | Probable mitochondrial intermembrane chaperone that participates in the import and insertion of some multi-pass transmembrane proteins into the mitochondrial inner membrane. Also required for the transfer of beta-barrel precursors from the TOM complex to the sorting and assembly machinery (SAM complex) of the outer membrane. Acts as a chaperone-like protein that protects the hydrophobic precursors from aggregation and guide them through the mitochondrial intermembrane space. |
Protein Name | Mitochondrial Import Inner Membrane Translocase Subunit Tim8 BDdp-Like ProteinDeafness Dystonia Protein 2 |
Database Links | Reactome: R-HSA-1268020 |
Cellular Localisation | Mitochondrion Inner MembranePeripheral Membrane ProteinIntermembrane Side |
Alternative Antibody Names | Anti-Mitochondrial Import Inner Membrane Translocase Subunit Tim8 B antibodyAnti-Ddp-Like Protein antibodyAnti-Deafness Dystonia Protein 2 antibodyAnti-TIMM8B antibodyAnti-DDP2 antibodyAnti-DDPL antibodyAnti-TIM8B antibody |
Information sourced from Uniprot.org