| Host: |
Rabbit |
| Applications: |
WB |
| Reactivity: |
Human/Mouse |
| Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description: |
Rabbit polyclonal antibody anti-TIAF1 (1-115) is suitable for use in Western Blot research applications. |
| Clonality: |
Polyclonal |
| Conjugation: |
Unconjugated |
| Isotype: |
IgG |
| Formulation: |
PBS with 0.02% Sodium Azide, 50% Glycerol, pH7.3. |
| Purification: |
Affinity purification |
| Dilution Range: |
WB 1:500-1:2000 |
| Storage Instruction: |
Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: |
MYO18AUniprot ID=TIAF1_HUMAN" |
| Immunogen Region: |
1-115 |
| Immunogen: |
Recombinant fusion protein containing a sequence corresponding to amino acids 1-115 of human TIAF1 (NP_004731.2). |
| Immunogen Sequence: |
MSSPSSPFREQSFLCAAGDA GEESRVQVLKNEVRRGSPVL LGWVEQAYADKCVCGPSAPP APTPPSLSQRVMCNDLFKVN PFQLQQFRADPSTASLLLCP GGLDHKLNLRGKAWG |
| Tissue Specificity | Not detectable in normal kidney and liver. Up-regulated in chronic and acute allograft rejection: expressed in the inflammatory infiltrate and in tubular epithelial cells. |
| Function | Isoform TIAF1: Inhibits the cytotoxic effects of TNF-alpha and overexpressed TNF receptor adapters TRADD, FADD, and RIPK1. Involved in TGF-beta1 inhibition of IkappaB-alpha expression and suppression of TNF-mediated IkappaB-alpha degradation. |
| Protein Name | Putative Tgfb1-Induced Anti-Apoptotic Factor 112 Kda Tgf-Beta-1-Induced Antiapoptotic Factor |
| Cellular Localisation | Isoform Tiaf1: Nucleus |
| Alternative Antibody Names | Anti-Putative Tgfb1-Induced Anti-Apoptotic Factor 1 antibodyAnti-12 Kda Tgf-Beta-1-Induced Antiapoptotic Factor antibodyAnti-MYO18A antibodyAnti-TIAF1 antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
