| Host: |
Rabbit |
| Applications: |
WB |
| Reactivity: |
Mouse |
| Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description: |
Rabbit polyclonal antibody anti-SPRY1 (1-170) is suitable for use in Western Blot research applications. |
| Clonality: |
Polyclonal |
| Conjugation: |
Unconjugated |
| Isotype: |
IgG |
| Formulation: |
PBS with 0.02% Sodium Azide, 50% Glycerol, pH7.3. |
| Purification: |
Affinity purification |
| Dilution Range: |
WB 1:500-1:2000 |
| Storage Instruction: |
Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: |
SPRY1 |
| Gene ID: |
10252 |
| Uniprot ID: |
SPY1_HUMAN |
| Immunogen Region: |
1-170 |
| Immunogen: |
Recombinant fusion protein containing a sequence corresponding to amino acids 1-170 of human SPRY1 (NP_005832.1). |
| Immunogen Sequence: |
MDPQNQHGSGSSLVVIQQPS LDSRQRLDYEREIQPTAILS LDQIKAIRGSNEYTEGPSVV KRPAPRTAPRQEKHERTHEI IPINVNNNYEHRHTSHLGHA VLPSNARGPILSRSTSTGSA ASSGSNSSASSEQGLLGRSP PTRPVPGHRSERAIRTQPKQ LIVDDLKGSL |
| Function | Inhibits fibroblast growth factor (FGF)-induced retinal lens fiber differentiation, probably by inhibiting FGF-mediated phosphorylation of ERK1/2. Inhibits TGFB-induced epithelial-to-mesenchymal transition in lens epithelial cells. |
| Protein Name | Protein Sprouty Homolog 1Spry-1 |
| Database Links | Reactome: R-HSA-182971 |
| Cellular Localisation | CytoplasmMembranePeripheral Membrane ProteinFound In The Cytoplasm In Unstimulated Cells But Is Translocated To The Membrane Ruffles In Cells Stimulated With Egf (Epidermal Growth Factor) |
| Alternative Antibody Names | Anti-Protein Sprouty Homolog 1 antibodyAnti-Spry-1 antibodyAnti-SPRY1 antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
