| Host: |
Rabbit |
| Applications: |
WB |
| Reactivity: |
Human |
| Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description: |
Rabbit polyclonal antibody anti-SLC25A15 (1-301) is suitable for use in Western Blot research applications. |
| Clonality: |
Polyclonal |
| Conjugation: |
Unconjugated |
| Isotype: |
IgG |
| Formulation: |
PBS with 0.02% Sodium Azide, 50% Glycerol, pH7.3. |
| Purification: |
Affinity purification |
| Dilution Range: |
WB 1:200-1:2000 |
| Storage Instruction: |
Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: |
SLC25A15 |
| Gene ID: |
10166 |
| Uniprot ID: |
ORNT1_HUMAN |
| Immunogen Region: |
1-301 |
| Immunogen: |
Recombinant fusion protein containing a sequence corresponding to amino acids 1-301 of human SLC25A15 (NP_055067.1). |
| Immunogen Sequence: |
MKSNPAIQAAIDLTAGAAGG TACVLTGQPFDTMKVKMQTF PDLYRGLTDCCLKTYSQVGF RGFYKGTSPALIANIAENSV LFMCYGFCQQVVRKVAGLDK QAKLSDLQNAAAGSFASAFA ALVLCPTELVKCRLQTMYEM ETSGKIAKSQNTVWSVIKSI LRKDGPLGFYHGLSSTLLRE VPGYFFFFGGYELSRSFFAS GRSKDELGPVPLMLSGGVGG ICLWLAVYPVDCIKSRIQV |
| Tissue Specificity | Highly expressed in liver, pancreas, testis, lung and small intestine. Lower levels are detected in spleen, kidney, brain and heart. |
| Function | Mitochondrial ornithine-citrulline antiporter (Probable). Catalyzes the exchange between cytosolic ornithine and mitochondrial citrulline plus an H(+), the proton compensates the positive charge of ornithine thus leading to an electroneutral transport. Plays a crucial role in the urea cycle, by connecting the cytosolic and the intramitochondrial reactions of the urea cycle (Probable). Lysine and arginine are also transported by the antiport mechanism (Probable). In addition, catalyzes an electroneutral exchange of ornithine or lysine for H(+), a reaction driven by the pH gradient across the inner membrane. |
| Protein Name | Mitochondrial Ornithine Transporter 1Solute Carrier Family 25 Member 15 |
| Database Links | Reactome: R-HSA-70635 |
| Cellular Localisation | Mitochondrion Inner MembraneMulti-Pass Membrane ProteinMitochondrion Membrane |
| Alternative Antibody Names | Anti-Mitochondrial Ornithine Transporter 1 antibodyAnti-Solute Carrier Family 25 Member 15 antibodyAnti-SLC25A15 antibodyAnti-ORC1 antibodyAnti-ORNT1 antibodyAnti-SP1855 antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
