| Host: |
Rabbit |
| Applications: |
WB |
| Reactivity: |
Human |
| Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description: |
Rabbit polyclonal antibody anti-PDCL (1-301) is suitable for use in Western Blot research applications. |
| Clonality: |
Polyclonal |
| Conjugation: |
Unconjugated |
| Isotype: |
IgG |
| Formulation: |
PBS with 0.01% Thimerosal, 50% Glycerol, pH7.3. |
| Purification: |
Affinity purification |
| Dilution Range: |
WB 1:500-1:2000 |
| Storage Instruction: |
Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: |
PDCL |
| Gene ID: |
5082 |
| Uniprot ID: |
PHLP_HUMAN |
| Immunogen Region: |
1-301 |
| Immunogen: |
Recombinant fusion protein containing a sequence corresponding to amino acids 1-301 of human PDCL (NP_005379.3). |
| Immunogen Sequence: |
MTTLDDKLLGEKLQYYYSSS EDEDSDHEDKDRGRCAPASS SVPAEAELAGEGISVNTGPK GVINDWRRFKQLETEQREEQ CREMERLIKKLSMTCRSHLD EEEEQQKQKDLQEKISGKMT LKEFAIMNEDQDDEEFLQQY RKQRMEEMRQQLHKGPQFKQ VFEISSGEGFLDMIDKEQKS IVIMVHIYEDGIPGTEAMNG CMICLAAEYPAVKFCKVKSS VIGASSQFTRNALPALLIY |
| Function | Acts as a positive regulator of hedgehog signaling and regulates ciliary function. Isoform 1: Functions as a co-chaperone for CCT in the assembly of heterotrimeric G protein complexes, facilitates the assembly of both Gbeta-Ggamma and RGS-Gbeta5 heterodimers. Isoform 2: Acts as a negative regulator of heterotrimeric G proteins assembly by trapping the preloaded G beta subunits inside the CCT chaperonin. |
| Protein Name | Phosducin-Like ProteinPhlp |
| Database Links | Reactome: R-HSA-6814122 |
| Cellular Localisation | Cell ProjectionCilium |
| Alternative Antibody Names | Anti-Phosducin-Like Protein antibodyAnti-Phlp antibodyAnti-PDCL antibodyAnti-PHLOP1 antibodyAnti-PhLP1 antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
