| Host: |
Rabbit |
| Applications: |
WB |
| Reactivity: |
Mouse/Rat |
| Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description: |
Rabbit polyclonal antibody anti-RIT2 (1-217) is suitable for use in Western Blot research applications. |
| Clonality: |
Polyclonal |
| Conjugation: |
Unconjugated |
| Isotype: |
IgG |
| Formulation: |
PBS with 0.01% Thimerosal, 50% Glycerol, pH7.3. |
| Purification: |
Affinity purification |
| Dilution Range: |
WB 1:500-1:2000 |
| Storage Instruction: |
Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: |
RIT2 |
| Gene ID: |
6014 |
| Uniprot ID: |
RIT2_HUMAN |
| Immunogen Region: |
1-217 |
| Immunogen: |
Recombinant fusion protein containing a sequence corresponding to amino acids 1-217 of human RIT2 (NP_002921.1). |
| Immunogen Sequence: |
MEVENEASCSPGSASGGSRE YKVVMLGAGGVGKSAMTMQF ISHQFPDYHDPTIEDAYKTQ VRIDNEPAYLDILDTAGQAE FTAMREQYMRGGEGFIICYS VTDRQSFQEAAKFKELIFQV RHTYEIPLVLVGNKIDLEQF RQVSTEEGLSLAQEYNCGFF ETSAALRFCIDDAFHGLVRE IRKKESMPSLMEKKLKRKDS LWKKLKGSLKKKRENMT |
| Tissue Specificity | Neuron-specific. |
| Function | Binds and exchanges GTP and GDP. Binds and modulates the activation of POU4F1 as gene expression regulator. |
| Protein Name | Gtp-Binding Protein Rit2Ras-Like Protein Expressed In NeuronsRas-Like Without Caax Protein 2 |
| Database Links | Reactome: R-HSA-187706 |
| Cellular Localisation | NucleusCell MembraneColocalizes With Plxnb3 At The Plasma Membrane |
| Alternative Antibody Names | Anti-Gtp-Binding Protein Rit2 antibodyAnti-Ras-Like Protein Expressed In Neurons antibodyAnti-Ras-Like Without Caax Protein 2 antibodyAnti-RIT2 antibodyAnti-RIN antibodyAnti-ROC2 antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
