Anti-Recombinant-PTPRR antibody [RM2G16] (STJA0025584)

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STJA0025584
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Host: Rabbit
Applications: IHC/WB
Reactivity: Human/Mouse/Rat
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description : Rabbit monoclonal antibody anti-Recombinant-Receptor-Type Tyrosine-Protein Phosphatase R is suitable for use in Immunohistochemistry and Western Blot research applications.
Clonality : Monoclonal
Clone ID : RM2G16
Conjugation: Unconjugated
Isotype: IgG
Formulation: 0.01M PBS, pH 7.4, 0.05% BSA, 50% Glycerol, 0.05% Sodium azide
Purification: Protein A/G purified from cell culture supernatant
Dilution Range: IHC: 1:100-1:200, WB: 1:1000-1:2000
Storage Instruction: Suitable for storage at +4°C between 1-2 weeks. For longer term store at-20°C for up to 12 months.
Gene Symbol: PTPRR
Gene ID: 5801
Uniprot ID: PTPRR_HUMAN
Function Sequesters mitogen-activated protein kinases (MAPKs) such as MAPK1, MAPK3 and MAPK14 in the cytoplasm in an inactive form. The MAPKs bind to a dephosphorylated kinase interacting motif, phosphorylation of which by the protein kinase A complex releases the MAPKs for activation and translocation into the nucleus.
Protein Name Receptor-Type Tyrosine-Protein Phosphatase R
R-Ptp-R
Ch-1ptpase
Nc-Ptpcom1
Protein-Tyrosine Phosphatase Pcptp1
Cellular Localisation Secreted
Isoform Alpha: Cell Membrane
Single-Pass Type I Membrane Protein
Isoform Delta: Cytoplasm
Perinuclear Region
Locates To The Perinuclear Areas Within The Cytoplasm
Isoform Gamma: Cytoplasm
Alternative Antibody Names Anti-Receptor-Type Tyrosine-Protein Phosphatase R antibody
Anti-R-Ptp-R antibody
Anti-Ch-1ptpase antibody
Anti-Nc-Ptpcom1 antibody
Anti-Protein-Tyrosine Phosphatase Pcptp1 antibody
Anti-PTPRR antibody
Anti-ECPTP antibody
Anti-PTPRQ antibody

Information sourced from Uniprot.org