| Host: |
Rabbit |
| Applications: |
WB |
| Reactivity: |
Human/Mouse/Rat |
| Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description: |
Rabbit polyclonal antibody anti-PPP1R13B (1-350) is suitable for use in Western Blot research applications. |
| Clonality: |
Polyclonal |
| Conjugation: |
Unconjugated |
| Isotype: |
IgG |
| Formulation: |
PBS with 0.01% Thimerosal, 50% Glycerol, pH7.3. |
| Purification: |
Affinity purification |
| Dilution Range: |
WB 1:200-1:2000 |
| Storage Instruction: |
Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: |
PPP1R13B |
| Gene ID: |
23368 |
| Uniprot ID: |
ASPP1_HUMAN |
| Immunogen Region: |
1-350 |
| Immunogen: |
Recombinant fusion protein containing a sequence corresponding to amino acids 1-350 of human PPP1R13B (NP_056131.2). |
| Immunogen Sequence: |
MMPMILTVFLSNNEQILTEV PITPETTCRDVVEFCKEPGE GSCHLAEVWRGNERPIPFDH MMYEHLQKWGPRREEVKFFL RHEDSPTENSEQGGRQTQEQ RTQRNVINVPGEKRTENGVG NPRVELTLSELQDMAARQQQ QIENQQQMLVAKEQRLHFLK QQERRQQQSISENEKLQKLK ERVEAQENKLKKIRAMRGQV DYSKIMNGNLSAEIERFSAM FQEKKQEVQTAILRVDQLS |
| Tissue Specificity | Reduced expression in breast carcinomas expressing a wild-type TP53 protein. |
| Function | Regulator that plays a central role in regulation of apoptosis via its interaction with p53/TP53. Regulates TP53 by enhancing the DNA binding and transactivation function of TP53 on the promoters of proapoptotic genes in vivo. |
| Protein Name | Apoptosis-Stimulating Of P53 Protein 1Protein Phosphatase 1 Regulatory Subunit 13b |
| Database Links | Reactome: R-HSA-139915Reactome: R-HSA-6803204Reactome: R-HSA-6803205Reactome: R-HSA-6803211Reactome: R-HSA-6804759 |
| Cellular Localisation | CytoplasmNucleusPredominantly CytoplasmicSome Fraction Is Nuclear |
| Alternative Antibody Names | Anti-Apoptosis-Stimulating Of P53 Protein 1 antibodyAnti-Protein Phosphatase 1 Regulatory Subunit 13b antibodyAnti-PPP1R13B antibodyAnti-ASPP1 antibodyAnti-KIAA0771 antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
