| Host: |
Rabbit |
| Applications: |
WB |
| Reactivity: |
Human |
| Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description: |
Rabbit polyclonal antibody anti-PES1 (1-150) is suitable for use in Western Blot research applications. |
| Clonality: |
Polyclonal |
| Conjugation: |
Unconjugated |
| Isotype: |
IgG |
| Formulation: |
PBS with 0.01% Thimerosal, 50% Glycerol, pH7.3. |
| Purification: |
Affinity purification |
| Dilution Range: |
WB 1:500-1:2000 |
| Storage Instruction: |
Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: |
PES1 |
| Gene ID: |
23481 |
| Uniprot ID: |
PESC_HUMAN |
| Immunogen Region: |
1-150 |
| Immunogen: |
Recombinant fusion protein containing a sequence corresponding to amino acids 1-150 of human PES1 (NP_055118.1). |
| Immunogen Sequence: |
MGGLEKKKYERGSATNYITR NKARKKLQLSLADFRRLCIL KGIYPHEPKHKKKVNKGSTA ARTFYLIKDIRFLLHEPIVN KFREYKVFVRKLRKAYGKSE WNTVERLKDNKPNYKLDHII KERYPTFIDALRDLDDALSM CFLFSTFPRT |
| Tissue Specificity | Significant levels are detected in a variety of cancer cell lines, including glioblastoma, breast carcinoma, colon carcinoma and cervical carcinoma cells. Levels are abnormally elevated in malignant tumors of astrocytic origin. |
| Post Translational Modifications | Sumoylated. |
| Function | Component of the PeBoW complex, which is required for maturation of 28S and 5.8S ribosomal RNAs and formation of the 60S ribosome. |
| Protein Name | Pescadillo Homolog |
| Database Links | Reactome: R-HSA-6791226 |
| Cellular Localisation | NucleusNucleolusNucleoplasmChromosomeAppears To Localize To The Periphery Of Metaphase Chromosomes During Mitosis And To The Prenucleolar Bodies That Form In Mitotic Cells Prior To The Actual Nucleoli |
| Alternative Antibody Names | Anti-Pescadillo Homolog antibodyAnti-PES1 antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
