| Host: |
Rabbit |
| Applications: |
WB/IHC |
| Reactivity: |
Human/Mouse/Rat |
| Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description: |
Rabbit polyclonal antibody anti-MLLT4 (1510-1680) is suitable for use in Western Blot and Immunohistochemistry research applications. |
| Clonality: |
Polyclonal |
| Conjugation: |
Unconjugated |
| Isotype: |
IgG |
| Formulation: |
PBS with 0.01% Thimerosal, 50% Glycerol, pH7.3. |
| Purification: |
Affinity purification |
| Dilution Range: |
WB 1:500-1:1000IHC-P 1:50-1:200 |
| Storage Instruction: |
Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: |
AFDN |
| Gene ID: |
4301 |
| Uniprot ID: |
AFAD_HUMAN |
| Immunogen Region: |
1510-1680 |
| Immunogen: |
Recombinant fusion protein containing a sequence corresponding to amino acids 1510-1680 of human MLLT4 (NP_001353249.1). |
| Immunogen Sequence: |
SLSPDPWKRDAKEKLEKQQQ MHIVDMLSKEIQELQSKPDR SAEESDRLRKLMLEWQFQKR LQESKQKDEDDEEEEDDDVD TMLIMQRLEAERRARLQDEE RRRQQQLEEMRKREAEDRAR QEEERRRQEEERTKRDAEEK RRQEEGYYSRLEAERRRQHD EAARRLLEPEA |
| Function | Belongs to an adhesion system, probably together with the E-cadherin-catenin system, which plays a role in the organization of homotypic, interneuronal and heterotypic cell-cell adherens junctions (AJs). Nectin- and actin-filament-binding protein that connects nectin to the actin cytoskeleton. May play a key role in the organization of epithelial structures of the embryonic ectoderm. Essential for the organization of adherens junctions. |
| Protein Name | AfadinAll1-Fused Gene From Chromosome 6 ProteinProtein Af-6Afadin Adherens Junction Formation Factor |
| Database Links | Reactome: R-HSA-418990 P55196-2 |
| Cellular Localisation | Cell JunctionAdherens JunctionNot Found At Cell-Matrix Ajs |
| Alternative Antibody Names | Anti-Afadin antibodyAnti-All1-Fused Gene From Chromosome 6 Protein antibodyAnti-Protein Af-6 antibodyAnti-Afadin Adherens Junction Formation Factor antibodyAnti-AFDN antibodyAnti-AF6 antibodyAnti-MLLT4 antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
